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原发性颅内滑膜肉瘤伴出血:一例报告。

Primary intracranial synovial sarcoma with hemorrhage: A case report.

作者信息

Wang Yang-Yang, Li Man-Li, Zhang Zhi-Yong, Ding Jiang-Wei, Xiao Li-Fei, Li Wen-Chao, Wang Lei, Sun Tao

机构信息

Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750000, Ningxia Hui Autonomous Region, China.

Sanquan College, Xinxiang Medical University, Xinxiang 453000, Henan Province, China.

出版信息

World J Clin Cases. 2021 Oct 16;9(29):8871-8878. doi: 10.12998/wjcc.v9.i29.8871.

Abstract

BACKGROUND

Synovial sarcoma (SS) is a highly malignant tumor of unknown histological origin. This tumor can occur in various parts of the body, including those without synovial structures, but mainly in and around the joints, mostly in the lower extremities. Primary intracranial SSs are remarkably rare. This paper aims to report a case of primary intracranial SS with hemorrhage.

CASE SUMMARY

A 35-year-old male patient suffered a headache and slurred speech during manual labor and was sent to the emergency department. Through imaging examination, the patient was considered to have high-grade glioma complicated with hemorrhage and was treated with craniotomy. Postoperative pathology revealed SS. positron emission tomography/computed tomography was performed, which ruled out the possibility of metastasis to the intracranial from other parts of the body. Postoperative radiotherapy was given to the patient, during which radiation necrosis occurred. Sixteen months after craniotomy, cranial magnetic resonance imaging revealed recurrence of the tumor.

CONCLUSION

Primary intracranial SS is a rare malignant tumor. Primary intracranial SS with hemorrhage and radiation necrosis should be carefully monitored during postoperative radiotherapy. Surgical resection of the tumor combined with postoperative radiotherapy and chemotherapy is currently used, but the prognosis is poor.

摘要

背景

滑膜肉瘤(SS)是一种组织学起源不明的高度恶性肿瘤。该肿瘤可发生于身体的各个部位,包括那些没有滑膜结构的部位,但主要发生在关节内及周围,多见于下肢。原发性颅内滑膜肉瘤极为罕见。本文旨在报告一例原发性颅内滑膜肉瘤伴出血的病例。

病例摘要

一名35岁男性患者在体力劳动时出现头痛和言语不清,被送往急诊科。通过影像学检查,该患者被认为患有高级别胶质瘤合并出血,并接受了开颅手术治疗。术后病理显示为滑膜肉瘤。进行了正电子发射断层扫描/计算机断层扫描,排除了身体其他部位转移至颅内的可能性。患者接受了术后放疗,在此期间发生了放射性坏死。开颅术后16个月,头颅磁共振成像显示肿瘤复发。

结论

原发性颅内滑膜肉瘤是一种罕见的恶性肿瘤。原发性颅内滑膜肉瘤伴出血和放射性坏死在术后放疗期间应密切监测。目前采用手术切除肿瘤并结合术后放疗和化疗,但预后较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a58/8546809/b1a2ab67db03/WJCC-9-8871-g001.jpg

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