Wu Bin, Li Ke, Chen Xiao-Fen, Zhang Jie, Wang Jing, Xiang Yue, Zhou Hong-Gui
Reproductive Medicine Centre, Department of Obstetrics and Gynecology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.
Department of Pathology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.
World J Clin Cases. 2021 Oct 16;9(29):8894-8900. doi: 10.12998/wjcc.v9.i29.8894.
Ovarian pregnancy after assisted reproductive technology treatment has rarely been reported; ovarian pregnancy following intrauterine insemination (IUI) is even rarer, and only nine cases have previously been reported.
We report a case of ovarian pregnancy rupture after ovulation induction and IUI. The patient presented with bilateral lower abdominal pain and was referred to the emergency department. Ultrasound examination revealed ovarian pregnancy and intraperitoneal bleeding. Laparoscopy revealed an ovarian pregnancy with hemoperitoneum, which was subsequently removed. Pelvic adhesions were detected intraoperatively, which were treated immediately. The patient spontaneously conceived an intrauterine pregnancy 3 mo later, which was ongoing at the time of writing this study.
Close attention should be paid to any history of pelvic inflammatory disease before commencing IUI treatment,and patients with such a history should be closely followed up after IUI. Early measurement of serum β-human chorionic gonadotropin levels and ultrasonic examination are essential for timely diagnosis of ovarian pregnancy after ovulation induction and IUI to avoid more serious complications.
辅助生殖技术治疗后发生卵巢妊娠的报道很少;宫内人工授精(IUI)后发生卵巢妊娠的情况更为罕见,此前仅有9例报道。
我们报告1例促排卵及IUI后卵巢妊娠破裂的病例。患者出现双侧下腹部疼痛,被转诊至急诊科。超声检查显示为卵巢妊娠及腹腔内出血。腹腔镜检查发现卵巢妊娠伴腹腔积血,随后将其切除。术中发现盆腔粘连并立即进行了处理。患者在3个月后自然受孕,在撰写本研究时妊娠仍在继续。
在开始IUI治疗前应密切关注盆腔炎病史,有此类病史的患者在IUI后应密切随访。早期测定血清β-人绒毛膜促性腺激素水平及超声检查对于促排卵及IUI后卵巢妊娠的及时诊断至关重要,可避免更严重的并发症。