常见可变免疫缺陷疾病：全科医生应了解的内容。
Common variable immunodeficiency disorders: What generalists should know.
作者信息
Jeevarathnum A C, van Niekerk A, Kriel J, Green R J
机构信息
Department of Paediatric Pulmonology, Faculty of Health Sciences, University of Pretoria, South Africa.
Sandton Allergy and Immunology Centre, Johannesburg, South Africa.
出版信息
Afr J Thorac Crit Care Med. 2021 Oct 4;27(3). doi: 10.7196/AJTCCM.2021.v27i3.228. eCollection 2021.
Abstract
Primary immune deficiency disorders (PIDDs) are common and underdiagnosed. Predominant antibody deficiencies (PADs) are the most common type of immune deficiency and comprise 55% of the immune deficiencies diagnosed. Although immunoglobulin A (IgA) deficiency remains the most common type of PID, common variable immunodeficiency disorders remain the most common symptomatic PID for which medical therapy is sought.
摘要
原发性免疫缺陷病（PIDDs）很常见且诊断不足。主要抗体缺陷（PADs）是最常见的免疫缺陷类型，占已诊断免疫缺陷的55%。虽然免疫球蛋白A（IgA）缺乏仍是最常见的原发性免疫缺陷类型，但常见变异型免疫缺陷病仍是寻求医学治疗的最常见有症状的原发性免疫缺陷病。
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本文引用的文献
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J Allergy Clin Immunol Pract. 2016 Jan-Feb;4(1):38-59. doi: 10.1016/j.jaip.2015.07.025. Epub 2015 Nov 7.
2
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Ann Allergy Asthma Immunol. 2014 Oct;113(4):452-9. doi: 10.1016/j.anai.2014.04.024. Epub 2014 May 29.
3
New diagnostic criteria for CVID.CVID 的新诊断标准。
Expert Rev Clin Immunol. 2014 Feb;10(2):183-6. doi: 10.1586/1744666X.2014.875274.
4
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Am J Rhinol Allergy. 2013 Jul-Aug;27(4):260-5. doi: 10.2500/ajra.2013.27.3899.
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