Division of Neurosurgery, Santa Maria Delle Grazie Hospital, AslNa2Nord, 80078, Pozzuoli, Italy.
Department of Neuroscience and Reproductive and Dental Sciences, Division of Neurosurgery, Università Degli Studi Di Napoli Federico II, Via Pansini 5, 80131, Naples, Italy.
Neurosurg Rev. 2022 Apr;45(2):1217-1232. doi: 10.1007/s10143-021-01684-1. Epub 2021 Nov 4.
Hemostasis in neurosurgery is of utmost importance. Bleeding management is one of the crucial steps of each neurosurgical procedure. Several strategies, namely thermal, mechanical, electric, and chemical, have been advocated to face blood loss within the surgical field. Over time, countless hemostatic agents and devices have been proposed. Furthermore, the ever-growing recent technological innovation has made available several novel and interesting tools. Pursuant to their impact on surgical practice, we perceived the imperative to update our previous disclosure paper. Therefore, we reviewed the literature and analyzed technical data sheets of each product in order to provide an updated and comprehensive overview in regard to chemical properties, mechanisms of action, use, complications, tricks, and pitfalls of topical hemostatic agents.
神经外科学中的止血至关重要。出血管理是每个神经外科手术过程中的关键步骤之一。已经提倡了几种策略，即热、机械、电和化学，以应对手术区域内的失血。随着时间的推移，已经提出了无数的止血剂和设备。此外，最近不断增长的技术创新提供了一些新颖有趣的工具。根据它们对手术实践的影响，我们认为有必要更新我们之前的披露文件。因此，我们回顾了文献，并分析了每种产品的技术数据表，以便提供关于局部止血剂的化学性质、作用机制、用途、并发症、技巧和陷阱的最新和全面的概述。
