Department of Medicine, Section of Infectious Diseases, Boston University School of Medicine and Boston Medical Center, Boston, MA (LH, SAA); Department of Medicine, Section of General Internal Medicine, Boston University School of Medicine and Boston Medical Center, Boston, MA (JLT, AYW); Boston Medical Center, Boston, MA (JK) and Department of Emergency Medicine, Boston University School of Medicine, Boston, MA (EMSP, EB).
J Addict Med. 2021;15(6):461-467. doi: 10.1097/ADM.0000000000000801.
To study the infection-related needs of patients with substance use disorders initiating care at a low-barrier-to-access program (LBAP) by describing the proportion with human immunodeficiency virus (HIV), hepatitis B and C virus (HBV, HCV), syphilis, gonorrhea, and chlamydia and determining rates of treatment and/or linkage to care.
We reviewed the records of patients who completed an intake visit at an LBAP in Boston, MA during the first 9 months after implementation of a standardized intake laboratory panel (January 30, 2017-September 30, 2017).
Among 393 patients initiating care, 84.7% (n = 333) completed at least 1 screening test. Baseline rates of HIV (9/393, 2.3%), current or past HCV (151/393, 38.4%), and chronic HBV (2/393, 0.5%) were high. Sixty-one new, active infections were identified through screening, including 1 HIV, 3 syphilis, 4 gonorrhea, 3 chlamydia, 1 chronic, and 1 acute HBV, and 48 cases of viremic HCV. Many patients were nonimmune to HBV (102/270, 37.8%) and HAV (112/255, 43.9%). Among new diagnoses, treatment was documented in 88% of bacterial infections and linkage occurred in 0/1 HIV, 2/2 HBV (100.0%), and 16/48 HCV (33.3%) cases.
Patients initiating SUD care at an LBAP have substantial, unmet infection-related needs. Results justify the inclusion of comprehensive infection prevention, screening, and linkage-to-treatment protocols in LBAPs.
通过描述人类免疫缺陷病毒(HIV)、乙型和丙型肝炎病毒(HBV、HCV)、梅毒、淋病和衣原体的感染比例,以及确定治疗和/或与护理的联系率,来研究在低障碍获得(LBAP)计划中开始接受治疗的物质使用障碍患者的感染相关需求。
我们回顾了在马萨诸塞州波士顿的一个 LBAP 完成入组评估的患者记录,时间为实施标准化入组实验室检测(2017 年 1 月 30 日至 2017 年 9 月 30 日)后的头 9 个月。
在开始接受治疗的 393 名患者中,84.7%(n=333)至少完成了 1 次筛查检测。HIV(393 例患者中有 9 例,2.3%)、现症或既往 HCV(393 例患者中有 151 例,38.4%)和慢性 HBV(393 例患者中有 2 例,0.5%)的基线率很高。通过筛查发现了 61 例新的活动性感染,包括 1 例 HIV、3 例梅毒、4 例淋病、3 例衣原体、1 例慢性 HBV 和 1 例急性 HBV,以及 48 例 HCV 病毒血症。许多患者对 HBV(270 例中有 102 例,37.8%)和 HAV(255 例中有 112 例,43.9%)无免疫力。在新诊断中,细菌性感染的治疗记录率为 88%,但 1 例 HIV(100.0%)、2 例 HBV(100.0%)和 16 例 HCV(33.3%)患者进行了治疗。
在 LBAP 中开始接受物质使用障碍治疗的患者存在大量未满足的感染相关需求。结果证明,LBAP 应包含全面的感染预防、筛查和与治疗联系的方案。