NEOMED Department of Anatomy and Neurobiology, Northeast Ohio Medical University, 4209 State Route 44, PO Box 95, Rootstown, OH 44272, USA.
Department of Cell Biology and Neuroscience, Rowan School of Osteopathic Medicine, Stratford, NJ 08084, USA.
J Exp Biol. 2021 Nov 1;224(21). doi: 10.1242/jeb.243075. Epub 2021 Nov 4.
The function of a muscle is impacted by its line of action, activity timing and contractile characteristics when active, all of which have the potential to vary within a behavior. One function of the hyoid musculature is to move the hyoid bone during swallowing, yet we have little insight into how their lines of action and contractile characteristics might change during a swallow. We used an infant pig model to quantify the contractile characteristics of four hyoid muscles during a swallow using synchronized electromyography, fluoromicrometry and high-speed biplanar videofluoroscopy. We also estimated muscle line of action during a swallow using contrast-enhanced CT-scanned muscles animated to move with the hyoid bone and found that as the hyoid elevated, the line of action of the muscles attached to it became greater in depression. We also found that muscles acted eccentrically and concentrically, which was correlated with hyoid movement. This work contributes to our understanding of how the musculature powering feeding functions during swallowing.
肌肉的功能受其作用线、活动时间和收缩特性的影响，这些特性在行为过程中都有可能发生变化。舌骨肌的一个功能是在吞咽时移动舌骨，但我们对它们的作用线和收缩特性在吞咽过程中可能发生的变化知之甚少。我们使用婴儿猪模型，通过同步肌电图、荧光微测法和高速双平面荧光透视术来量化吞咽过程中四块舌骨肌的收缩特性。我们还使用对比增强 CT 扫描的肌肉来估计吞咽时的肌肉作用线，这些肌肉被动画化为与舌骨一起运动，结果发现，随着舌骨的抬起，附着其上的肌肉的作用线在下降方向上变得更大。我们还发现肌肉进行了离心和向心收缩，这与舌骨的运动有关。这项工作有助于我们理解在吞咽过程中为喂养功能提供动力的肌肉组织的工作方式。
