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Editorial Comment: Testosterone replacement therapy (TRT) and prostate cancer: An updated systematic review with a focus on previous or active localized prostate cancer.编辑评论：睾酮替代疗法（TRT）与前列腺癌：一项最新的系统评价，重点关注既往或现患局限性前列腺癌。
Int Braz J Urol. 2022 Jan-Feb;48(1):188-195. doi: 10.1590/S1677-5538.IBJU.2022.01.08.
2
Testosterone replacement therapy (TRT) and prostate cancer: An updated systematic review with a focus on previous or active localized prostate cancer.睾酮替代疗法（TRT）与前列腺癌：更新的系统评价，重点关注先前或活跃的局限性前列腺癌。
Urol Oncol. 2020 Aug;38(8):661-670. doi: 10.1016/j.urolonc.2020.04.008. Epub 2020 May 11.
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Testosterone replacement therapy in men with prostate cancer: a time-varying analysis.前列腺癌男性的睾酮替代疗法：一项时变分析。
J Sex Med. 2015 Feb;12(2):374-80. doi: 10.1111/jsm.12768. Epub 2014 Dec 11.
4
The effect of testosterone replacement therapy on prostate cancer: a systematic review and meta-analysis.睾酮替代疗法对前列腺癌的影响：一项系统评价与荟萃分析。
Prostate Cancer Prostatic Dis. 2014 Jun;17(2):132-43. doi: 10.1038/pcan.2013.60. Epub 2014 Jan 21.
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Testosterone replacement for hypogonadism after treatment of early prostate cancer with brachytherapy.近距离放射治疗早期前列腺癌后性腺功能减退的睾酮替代治疗。
Cancer. 2007 Feb 1;109(3):536-41. doi: 10.1002/cncr.22438.
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Prostate-specific antigen changes and prostate cancer in hypogonadal men treated with testosterone replacement therapy.接受睾酮替代疗法的性腺功能减退男性的前列腺特异性抗原变化与前列腺癌
BJU Int. 2009 May;103(9):1179-83. doi: 10.1111/j.1464-410X.2008.08240.x. Epub 2008 Dec 23.
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Testosterone replacement in prostate cancer survivors with hypogonadal symptoms.雄激素替代治疗有低雄激素症状的前列腺癌幸存者。
BJU Int. 2010 May;105(10):1397-401. doi: 10.1111/j.1464-410X.2009.08980.x. Epub 2009 Nov 11.
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Prostate magnetic resonance imaging findings in patients treated for testosterone deficiency while on active surveillance for low-risk prostate cancer.接受睾酮缺乏治疗且正在对低风险前列腺癌进行主动监测的患者的前列腺磁共振成像结果。
Urol Oncol. 2016 Dec;34(12):530.e9-530.e14. doi: 10.1016/j.urolonc.2016.07.004. Epub 2016 Sep 22.
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Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: results of 1 year of treatment in men with prostatic intraepithelial neoplasia.睾酮替代疗法用于前列腺癌高危性腺功能减退男性：前列腺上皮内瘤变男性患者1年治疗结果
J Urol. 2003 Dec;170(6 Pt 1):2348-51. doi: 10.1097/01.ju.0000091104.71869.8e.
10
Testosterone replacement therapy and the risk of prostate cancer. Is there a link?睾酮替代疗法与前列腺癌风险。存在关联吗？
Int J Impot Res. 2006 Jul-Aug;18(4):323-8. doi: 10.1038/sj.ijir.3901418. Epub 2005 Nov 10.

本文引用的文献

1
Oncological safety and functional outcomes of testosterone replacement therapy in symptomatic adult-onset hypogonadal prostate cancer patients following robot-assisted radical prostatectomy.雄激素替代治疗对机器人辅助根治性前列腺切除术后症状性成人迟发性性腺功能减退前列腺癌患者的肿瘤安全性和功能结局的影响。
World J Urol. 2021 Sep;39(9):3223-3229. doi: 10.1007/s00345-020-03475-7. Epub 2020 Oct 9.
2
Estrogen Receptors Promote Migration, Invasion and Colony Formation of the Androgen-Independent Prostate Cancer Cells PC-3 Through β-Catenin Pathway.雌激素受体通过β-连环蛋白通路促进雄激素非依赖性前列腺癌细胞 PC-3 的迁移、侵袭和集落形成。
Front Endocrinol (Lausanne). 2020 Apr 9;11:184. doi: 10.3389/fendo.2020.00184. eCollection 2020.
3
European Academy of Andrology (EAA) guidelines on investigation, treatment and monitoring of functional hypogonadism in males: Endorsing organization: European Society of Endocrinology.欧洲男科学会（EAA）关于男性功能性性腺功能减退的检查、治疗和监测指南：认可机构：欧洲内分泌学会。
Andrology. 2020 Sep;8(5):970-987. doi: 10.1111/andr.12770. Epub 2020 Mar 20.
4
Oncological safety of testosterone replacement therapy in prostate cancer survivors after definitive local therapy: A systematic literature review and meta-analysis.根治性局部治疗后前列腺癌幸存者睾酮替代治疗的肿瘤安全性：系统文献回顾和荟萃分析。
Urol Oncol. 2019 Oct;37(10):637-646. doi: 10.1016/j.urolonc.2019.06.007. Epub 2019 Jul 8.
5
Testosterone Replacement Therapy and the Risk of Prostate Cancer in Men With Late-Onset Hypogonadism.睾酮替代疗法与迟发性性腺功能减退症男性前列腺癌风险。
Am J Epidemiol. 2019 Sep 1;188(9):1666-1673. doi: 10.1093/aje/kwz138.
6
Testosterone Deficiency: A Review and Comparison of Current Guidelines.睾酮缺乏症：当前指南的综述与比较。
J Sex Med. 2019 Jun;16(6):812-820. doi: 10.1016/j.jsxm.2019.03.262. Epub 2019 May 9.
7
Evolution of Guidelines for Testosterone Replacement Therapy.睾酮替代疗法指南的演变
J Clin Med. 2019 Mar 25;8(3):410. doi: 10.3390/jcm8030410.
8
Testosterone, testosterone therapy and prostate cancer.睾酮、睾酮治疗与前列腺癌。
Aging Male. 2019 Dec;22(4):219-227. doi: 10.1080/13685538.2018.1524456. Epub 2019 Jan 7.
9
Evaluation and Treatment of Male Hypogonadism.男性性腺功能减退的评估与治疗
JAMA. 2018 Apr 3;319(13):1375-1376. doi: 10.1001/jama.2018.3182.
10
Testosterone Replacement Therapy and Risk of Favorable and Aggressive Prostate Cancer.睾酮替代疗法与良性及侵袭性前列腺癌风险
J Clin Oncol. 2017 May 1;35(13):1430-1436. doi: 10.1200/JCO.2016.69.5304. Epub 2017 Mar 13.

Editorial Comment: Testosterone replacement therapy (TRT) and prostate cancer: An updated systematic review with a focus on previous or active localized prostate cancer.

作者信息

Javaroni Valter

机构信息

Departamento de Andrologia, Hospital Federal do Andaraí, Rio de Janeiro, RJ, Brasil.

出版信息

Int Braz J Urol. 2022 Jan-Feb;48(1):188-195. doi: 10.1590/S1677-5538.IBJU.2022.01.08.

DOI:10.1590/S1677-5538.IBJU.2022.01.08
PMID:34735092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8691234/
Abstract
摘要