Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, 1-5-7, Asahimachi, Abenoku, Osaka City, Osaka, 545-8585, Japan.
Int Orthop. 2022 Feb;46(2):189-195. doi: 10.1007/s00264-021-05256-2. Epub 2021 Nov 3.
To verify changes in the health-related quality of life (HRQOL) of patients with musculoskeletal disorders after the coronavirus disease 2019 (COVID-19) pandemic and to assess the relationship between the patients' change in several activities of daily living and in the HRQOL to discover factors related to the deterioration in HRQOL.
A multi-centre cross-sectional questionnaire survey was administered between November 1, 2020, and December 31, 2020, in Japan. The participants included those who visited the orthopaedics clinic within the survey period and had experienced the first and second waves of COVID-19 in Japan and the first stay-at-home order issued by the government. Patients' HRQOL at the two different time points (pre-outbreak and post-second wave of COVID-19) was assessed with the EuroQoL-5 dimensions 5-level (EQ-5D).
The survey was completed by 1254 patients (average age: 52.5 ± 21.9 years; 644 women). Among them, 431 patients (34.3%) reported a decrease in the EQ-5D index after the pandemic. The largest decrease was in the pain domain followed by the mobility domain. Multivariate logistic regression analysis revealed that the patients with decreased regular exercise habits were significantly related to deterioration in HRQOL compared with those with stable regular exercise (adjusted odds ratio = 1.76, p < 0.001) independently from age, sex, and change of symptoms.
Up to 35% of patients with musculoskeletal disorders reported deterioration of HRQOL after the COVID-19 pandemic. Pain and mobility rather than anxiety were the two leading factors of the HRQOL decrease. The decrease in regular exercise was related to the HRQOL decrease.
验证 2019 年冠状病毒病（COVID-19）大流行后肌肉骨骼疾病患者健康相关生活质量（HRQOL）的变化，并评估患者日常生活活动变化与 HRQOL 之间的关系，以发现与 HRQOL 恶化相关的因素。
2020 年 11 月 1 日至 12 月 31 日，在日本进行了一项多中心横断面问卷调查。参与者包括在调查期间访问骨科诊所并经历了日本的第一波和第二波 COVID-19 以及政府发布的第一次居家令的患者。使用欧洲五维健康量表 5 级（EQ-5D）评估患者在两个不同时间点（疫情前和 COVID-19 第二波后）的 HRQOL。
共有 1254 名患者（平均年龄：52.5±21.9 岁；644 名女性）完成了调查。其中，431 名患者（34.3%）报告在大流行后 EQ-5D 指数下降。下降幅度最大的是疼痛域，其次是移动域。多变量逻辑回归分析显示，与保持稳定常规运动习惯的患者相比，常规运动习惯减少的患者 HRQOL 恶化显著相关（调整优势比=1.76，p<0.001），独立于年龄、性别和症状变化。
多达 35%的肌肉骨骼疾病患者在 COVID-19 大流行后报告 HRQOL 恶化。疼痛和移动性而不是焦虑是 HRQOL 下降的两个主要因素。常规运动的减少与 HRQOL 下降有关。
