Aarhus University, Center for Alcohol and Drug Research, Bartholins Allé 10, 8000 Aarhus C, Denmark.
Aarhus University, Department of Forensic Medicine, Palle Juul-Jensens Boulevard 99, Building Z, 3.017, 8200 Aarhus N, Denmark.
Forensic Sci Int. 2021 Dec;329:111050. doi: 10.1016/j.forsciint.2021.111050. Epub 2021 Oct 7.
Cocaine-related emergency department admissions are increasing, and cocaine seizures are at an all-time high in Europe. Our aim was to investigate the trends in purity and adulterants over time in cocaine available to cocaine users at street level in Denmark. We used a representative sample of cocaine seized at street level and analyzed by the national departments of forensic medicine between 2006 and 2019 (n = 1460). Latent profile analysis was used to classify the samples based on cocaine, levamisole, and phenacetin content. Low purity cocaine comprised most of the cocaine seizures in early years, but its share began to decline in 2013, and from 2016 to 2019, the high purity profile was dominant. While the total number of samples containing adulterants decreased, levamisole remained a common and dangerous adulterant. The findings underline the need to inform the public, medical doctors, and service providers for people with drug use disorders about the higher potency of street cocaine.
可卡因相关的急诊入院人数正在增加，欧洲的可卡因缉获量也达到了历史最高水平。我们的目的是调查在丹麦街头可卡因使用者可获得的可卡因的纯度和掺杂物随时间的变化趋势。我们使用了 2006 年至 2019 年期间国家法医部门在街头缉获的代表性可卡因样本（n=1460）进行分析。潜在剖面分析用于根据可卡因、左旋咪唑和非那西汀的含量对样本进行分类。低纯度可卡因在早期占据了大部分可卡因缉获量，但从 2013 年开始，其份额开始下降，2016 年至 2019 年期间，高纯度可卡因成为主要类型。虽然含有掺杂物的样本总数有所减少，但左旋咪唑仍然是一种常见且危险的掺杂物。这些发现强调了有必要向公众、医生和药物使用障碍患者的服务提供者告知街头可卡因的更高效力。
