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[人类免疫缺陷病毒感染中所见的口腔病变。II. 组织病理学和超微结构研究]

[Stomatological lesions seen in HIV virus infection. II. Histopathological and ultrastructural studies].

作者信息

Brocheriou C, D'Agay M F, Verola O, Cousteau C, Laufer J

出版信息

Rev Stomatol Chir Maxillofac. 1987;88(2):93-107.

PMID:3473605
Abstract

Buccal lesions observed in the clinical setting of human immunodeficiency virus (HIV) infection constitute a diverse group of pathological entities. Several are related to the opportunistic infections observed in association with HIV infection. "Hairy leukoplakia" is a recently described benign lesion that is presumably related to infection by Epstein-Barr virus (E.B.V.). Kaposi's sarcoma is seen somewhat frequently in the oral cavity, especially involving the palate of HIV infected patients. We have observed this lesion 19 times in this location. The diagnosis is usually relatively straight-forward. Both vascular inflammatory and more typical sarcomatous morphology sub-types are present. The salivary glands may show an important lymphoplasmocytic infiltration which is unusual in that associated epithelial changes are not observed. The salivary glands seem to be a seat of the lymphocytic infiltration seen in other organs during the course of HIV infection. As for the changes encountered in the lymph nodes in HIV infection, they represent different stages in the evolution of a dynamic process, which progresses from hyperplasia to atrophy of the lymph nodes.

摘要

在人类免疫缺陷病毒(HIV)感染的临床环境中观察到的口腔病变构成了一组多样的病理实体。其中一些与HIV感染相关的机会性感染有关。“毛状白斑”是一种最近描述的良性病变,推测与爱泼斯坦-巴尔病毒(E.B.V.)感染有关。卡波西肉瘤在口腔中较为常见,尤其累及HIV感染患者的腭部。我们在这个部位观察到这种病变19次。诊断通常相对简单。同时存在血管炎性和更典型的肉瘤形态亚型。唾液腺可能会出现重要的淋巴细胞浆细胞浸润,其不同寻常之处在于未观察到相关的上皮变化。唾液腺似乎是HIV感染过程中在其他器官中所见淋巴细胞浸润的部位。至于HIV感染时淋巴结出现的变化,它们代表了一个动态过程演变的不同阶段,该过程从淋巴结增生发展到萎缩。

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[Stomatological lesions seen in HIV virus infection. II. Histopathological and ultrastructural studies].[人类免疫缺陷病毒感染中所见的口腔病变。II. 组织病理学和超微结构研究]
Rev Stomatol Chir Maxillofac. 1987;88(2):93-107.
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