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先天性胆道闭锁/新生儿胆汁淤积症:未来的发展方向是什么?

Biliary Atresia/Neonatal Cholestasis: What is in the Horizon?

机构信息

Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, 3800 Reservoir Road, NW, Washington, DC, USA.

Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, 3800 Reservoir Road, NW, Washington, DC, USA; Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA.

出版信息

Pediatr Clin North Am. 2021 Dec;68(6):1333-1341. doi: 10.1016/j.pcl.2021.08.002.

Abstract

"Biliary atresia (BA) is a common cause of jaundice in infancy. There is increasing evidence that newborn screening with direct or conjugated bilirubin leads to earlier diagnosis. Although the Kasai portoenterostomy is the primary treatment, there are scientific advances in adjuvant therapies. As pediatric patients transition to adult care, multidisciplinary care is essential, given the complexity of this patient population."

摘要

先天性胆道闭锁(BA)是婴儿期黄疸的常见原因。越来越多的证据表明,直接或结合胆红素的新生儿筛查可导致更早的诊断。虽然 Kasai 门腔分流术是主要的治疗方法,但辅助治疗方面有科学进展。由于该患者群体的复杂性,儿科患者过渡到成人护理时,多学科护理至关重要。

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