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Does perioperative systemic therapy represent the optimal therapeutic paradigm in organ-confined, muscle-invasive urothelial carcinoma?

作者信息

Scafuri Luca, Sciarra Antonella, Crocetto Felice, Ferro Matteo, Buonerba Carlo, Ugliano Francesco, Guerra Germano, Sanseverino Roberto, Lorenzo Giuseppe Di

机构信息

Oncology Unit, Hospital 'Andrea Tortora,' ASL Salerno, Pagani, 84016, Italy.

Associazione O.R.A., Somma Vesuviana, Naples, Italy.

出版信息

Future Sci OA. 2021 Oct 28;7(9):FSO770. doi: 10.2144/fsoa-2021-0092. eCollection 2021 Oct.

DOI:10.2144/fsoa-2021-0092
PMID:34737893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8558855/
Abstract
摘要

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Neutrophil percentage-to-albumin ratio predicts mortality in bladder cancer patients treated with neoadjuvant chemotherapy followed by radical cystectomy.中性粒细胞与白蛋白比值可预测接受新辅助化疗后行根治性膀胱切除术的膀胱癌患者的死亡率。
Future Sci OA. 2021 Apr 20;7(7):FSO709. doi: 10.2144/fsoa-2021-0008. eCollection 2021 Aug.
2
Adjuvant Nivolumab versus Placebo in Muscle-Invasive Urothelial Carcinoma.纳武利尤单抗辅助治疗与安慰剂用于肌肉浸润性尿路上皮癌。
N Engl J Med. 2021 Jun 3;384(22):2102-2114. doi: 10.1056/NEJMoa2034442.
3
Three vs. Four Cycles of Neoadjuvant Chemotherapy for Localized Muscle Invasive Bladder Cancer Undergoing Radical Cystectomy: A Retrospective Multi-Institutional Analysis.接受根治性膀胱切除术的局限性肌层浸润性膀胱癌新辅助化疗三个周期与四个周期的比较：一项回顾性多机构分析
Front Oncol. 2021 May 11;11:651745. doi: 10.3389/fonc.2021.651745. eCollection 2021.
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Perioperative pembrolizumab therapy in muscle-invasive bladder cancer: Phase III KEYNOTE-866 and KEYNOTE-905/EV-303.肌层浸润性膀胱癌的围手术期帕博利珠单抗治疗：III 期 KEYNOTE-866 和 KEYNOTE-905/EV-303 研究。
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Minerva Urol Nefrol. 2020 Oct;72(5):641-643. doi: 10.23736/S0393-2249.20.03850-3. Epub 2020 Jun 16.