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三度房室传导阻滞的一种罕见可逆病因:一例病例报告

A rare and reversible cause of third-degree atrioventricular block: a case report.

作者信息

Lee Gino, Badertscher Patrick, Sticherling Christian, Osswald Stefan

机构信息

Department of Cardiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland.

出版信息

Eur Heart J Case Rep. 2021 Oct 18;5(10):ytab372. doi: 10.1093/ehjcr/ytab372. eCollection 2021 Oct.

Abstract

BACKGROUND

Cardiac involvement of Lyme disease (LD) typically results in atrioventricular (AV) conduction disturbance, mainly third-degree AV block.

CASE SUMMARY

A 54-year-old patient presented to our emergency department due to recurrent syncope. Third-degree AV block with a ventricular escape rhythm (33 b.p.m.) was identified as the underlying rhythm. Transthoracic echocardiography (TTE) was normal. To rule out common reversible causes of complete AV block, a screening test for Lyme borreliosis was carried out. Elevated levels for borrelia IgG/IgM were found and confirmed by western blot analysis. Lyme carditis (LC) was postulated as the most likely cause of the third-degree AV block given the young age of the patient. Initiation of antibiotic therapy with ceftriaxone resulted in a gradual normalization of the AV conduction with stable first-degree AV block on Day 6 of therapy. The patient was changed on oral antibiotics (doxycycline) and discharged without a pacemaker. After 3 months, the AV conduction recovered to normal.

DISCUSSION

Lyme carditis should always be considered, particularly in younger patients with new-onset AV block and without evidence of structural heart disease. Atrioventricular block recovers in the majority of cases after appropriate antibiotic treatment.

摘要

背景

莱姆病(LD)累及心脏时通常会导致房室(AV)传导障碍,主要是三度房室传导阻滞。

病例摘要

一名54岁患者因反复晕厥就诊于我院急诊科。潜在心律为三度房室传导阻滞伴心室逸搏心律(33次/分钟)。经胸超声心动图(TTE)检查正常。为排除完全性房室传导阻滞常见的可逆病因,进行了莱姆病螺旋体病筛查试验。发现伯氏疏螺旋体IgG/IgM水平升高,并经蛋白印迹分析证实。鉴于患者年轻,推测莱姆心肌炎(LC)是三度房室传导阻滞最可能的病因。开始使用头孢曲松进行抗生素治疗后,房室传导逐渐恢复正常,治疗第6天时一度房室传导阻滞稳定。患者改为口服抗生素(多西环素),未安装起搏器出院。3个月后,房室传导恢复正常。

讨论

应始终考虑莱姆心肌炎,特别是在新发房室传导阻滞且无结构性心脏病证据的年轻患者中。在大多数情况下,适当的抗生素治疗后房室传导阻滞会恢复。

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