Department of Hematology, Amsterdam UMC, University of Amsterdam, Cancer Center Amsterdam, Amsterdam.
LYMMCARE (Lymphoma and Myeloma Center Amsterdam), Amsterdam, the Netherlands.
Br J Haematol. 2022 Mar;196(5):1205-1208. doi: 10.1111/bjh.17926. Epub 2021 Nov 4.
Contemporary diagnosed WM patients, compared to the general population, continue to experience excess mortality regardless of having survived up to 15 years post-diagnosis. This gradual increase in excess mortality might result from the incurable nature of this disease characterized by multiple relapses throughout the disease course with limited efficacious treatment options in the released/refractory setting.
与一般人群相比，当代诊断为 WM 的患者即使在诊断后存活了 15 年以上，仍持续存在超额死亡率。这种超额死亡率的逐渐增加可能是由于这种疾病的不可治愈性质所致，其特征是在疾病过程中多次复发，而在缓解/难治性疾病中治疗选择有限。
