Department of Pulmonology, University of Health Sciences Atatürk Chest Diseases and Thoracic Surgery Education and Research Hospital, Ankara, Turkey.
Department of Pulmonology, Medical Faculty, Alanya Alaaddin Keykubat University, Alanya, Turkey.
Int J Clin Pract. 2021 Dec;75(12):e15002. doi: 10.1111/ijcp.15002. Epub 2021 Nov 12.
We aimed to evaluate the role of Rapid On-Site Evaluation (ROSE) in improving the diagnostic contribution of EBUS-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis of granulomatous lymphadenitis.
We retrospectively included all patients in the study who underwent EBUS-TBNA (n = 405) from September 2013 to September 2017. All cases who underwent EBUS-TBNA and were found to have "granuloma" in the final pathological diagnosis (n = 143) were included in the research.
One hundred forty-three cases who underwent EBUS and whose final pathological diagnosis was granuloma were included in the study. A total of 231 lymph nodes were sampled. The final diagnosis was found to be compatible with the examination during the procedure for 55 (85.9%) out of 64 patients for whom ROSE was performed. In addition, while 79.7% of the 64 patients who underwent ROSE were tested positive for granuloma, 9.4% were suspected to have granuloma, and no diagnostic result was obtained for 10.9%. The number of lymph node needle aspirations was statistically significantly lower in patients for whom ROSE was performed (P < .001). The final diagnosis was found to be compatible with the examination during the procedure for 55 (85.9%) out of 64 patients for whom ROSE was performed. According to the evaluation made on the duration, the procedure was completed in the first 15 minutes in 95.4% of the patients for whom ROSE was performed, while the procedure took longer than 15 minutes in 93.6% of the patients for whom ROSE was not performed.
We found a high incidence of congruence between ROSE and the final cytological diagnosis if granulomas were identified in the final cytology. Performing ROSE shortens the duration of the procedure and reduced sampling thus preventing complications that may occur due to prolongation of the procedure.
本研究旨在评估快速现场评估（ROSE）在提高经支气管超声引导针吸活检术（EBUS-TBNA）诊断肉芽肿性淋巴结炎中的诊断作用。
回顾性纳入 2013 年 9 月至 2017 年 9 月期间行 EBUS-TBNA 的所有患者（n=405）。纳入最终病理诊断为“肉芽肿”的所有 EBUS-TBNA 患者（n=143）。
共纳入 143 例行 EBUS 且最终病理诊断为肉芽肿的患者。共采集 231 个淋巴结。对 64 例行 ROSE 的患者，有 55 例（85.9%）最终诊断与术中检查结果一致。此外，在 64 例行 ROSE 的患者中，79.7%的患者肉芽肿检测阳性，9.4%的患者疑似肉芽肿，10.9%的患者未获得诊断结果。行 ROSE 的患者淋巴结针吸数明显减少（P<.001）。对 64 例行 ROSE 的患者，55 例（85.9%）最终诊断与术中检查结果一致。从耗时评估来看，95.4%的 ROSE 患者可在 15 分钟内完成检查，而 93.6%的未行 ROSE 患者的检查时间超过 15 分钟。
如果最终细胞学检查中发现肉芽肿，ROSE 与最终细胞学诊断的符合率较高。行 ROSE 可缩短操作时间，减少采样，从而预防因操作时间延长而导致的并发症。
