Divsions of Pediatric Critical Care Unit, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Divsions of Pediatric Cardiology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Turk J Pediatr. 2021;63(5):913-916. doi: 10.24953/turkjped.2021.05.020.
Beta blockers (BB) are used for very different indications in both adults and children. There can be mild adverse effects with normal doses. When taken in toxic doses, this can have fatal results in children. There are some standard therapies during BB poisoning such as insulin and glucagon but there is not enough knowledge concerning intravenous lipid infusion therapy (ILI).
Herein we present a case of propranolol poisoning in a previously healthy 2-year-old girl. In this patient, cardiac arrest developed twice, and cardiopulmonary resuscitation was performed for 5 and 20 minutes, respectively. We initiated inotropes, insulin, calcium and glucagon with a lack of response to all medical treatment. We used ILI and the patient improved after this treatment. She recovered without any disability.
ILI treatment should be considered with life-threatening BB poisoning which is unresponsive to standard therapies.
β受体阻滞剂（BB）在成人和儿童中的应用有很大的差异，其在正常剂量下可能会产生轻微的不良反应，而在服用中毒剂量时可能会对儿童产生致命的结果。在 BB 中毒的情况下，有一些标准的治疗方法，如胰岛素和胰高血糖素，但对于静脉内脂肪输注疗法（ILI）的了解还不够。
本文介绍了一例先前健康的 2 岁女孩服用普萘洛尔中毒的病例。该患者两次出现心脏骤停，分别进行了 5 分钟和 20 分钟的心肺复苏。我们使用了正性肌力药物、胰岛素、钙和胰高血糖素，但所有的治疗都没有反应。我们使用了 ILI，患者在接受治疗后有所改善。她没有任何残疾地康复了。
对于标准治疗方法无效的危及生命的 BB 中毒，应考虑使用 ILI 治疗。
