Austin M B, Frierson H F, Feldman P S
Acta Cytol. 1987 May-Jun;31(3):351-6.
An oncocytoid adenocarcinoma of the parotid gland, diagnosed by fine needle aspiration cytology, is reported. The neoplasm, seen in a 66-year-old man, metastasized to 33 of 46 resected cervical lymph nodes; the patient is currently free of disease 17 months after surgery. Cytologically, the neoplastic cells occurred singly and in small clusters. They had abundant granular cytoplasm with occasional vacuoles, large nuclei and prominent nucleoli. Ultrastructurally, the tumor cells had copious cytoplasm, with moderately increased numbers of mitochondria, dilated endoplasmic reticulum, mucin droplets and intracytoplasmic lumina. The clinical importance of distinguishing this neoplasm from true malignant oncocytoma is, at present, unknown.
报告了1例通过细针穿刺细胞学诊断的腮腺嗜酸性细胞腺癌。该肿瘤见于1名66岁男性，转移至46个切除的颈部淋巴结中的33个；患者术后17个月目前无疾病。细胞学上，肿瘤细胞单个或小簇状出现。它们具有丰富的颗粒状细胞质，偶尔有空泡，大细胞核和明显的核仁。超微结构上，肿瘤细胞有大量细胞质，线粒体数量适度增加，内质网扩张，有黏液滴和胞质内管腔。目前，将该肿瘤与真正的恶性嗜酸性细胞瘤区分开来的临床意义尚不清楚。
