XIAP 缺乏症中的潘氏细胞功能障碍与肠道微生物组。
Paneth cell dysfunction and the intestinal microbiome in XIAP deficiency.
机构信息
Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK.
Department of Paediatrics, University of Oxford, Oxford, UK.
出版信息
Sci Immunol. 2021 Nov 5;6(65):eabm0293. doi: 10.1126/sciimmunol.abm0293.
PMID:34739344
Abstract
New data suggest how epithelial dysfunction and intestinal dysbiosis contribute to inflammatory bowel disease in patients and in models of XIAP deficiency (see the related Research Articles by Strigli . and Wahida .).
摘要
新数据表明上皮功能障碍和肠道菌群失调如何导致 XIAP 缺乏症患者和模型中的炎症性肠病（参见 Strigli 和 Wahida 的相关研究文章）。
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