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一项前瞻性研究,旨在调查非索罗定治疗对急迫性尿失禁患者生活质量、焦虑和抑郁的影响。

A Prospective Study to Investigate the Effect of Fesoterodine Treatment on Quality of Life, Anxiety, and Depression in Urge-Type Urinary Incontinence.

机构信息

Gaziantep University, Faculty of Medicine, Department of Internal Medicine, 27100 Sahinbey, Gaziantep, Turkey.

出版信息

Urol J. 2021 Nov 4;19(1):69-74. doi: 10.22037/uj.v18i.6834.

DOI:10.22037/uj.v18i.6834
PMID:34739725
Abstract

PURPOSE

Urinary incontinence (UI) is a fundamental health problem, can occur at any age but is especially common in older women. Depression and anxiety are also considerable problems for the elderly. UI is one of the geriatric syndromes that are thought to be related to depression and quality of life (QOL).

MATERIALS AND METHODS

This prospective study was conducted for a period of 2 months from February 2020 to April 2020. Women who applied to the outpatient clinic of geriatrics with UI symptoms were taken into the study. The type of UI was determined by using the 3 Incontinence Questions (3IQ). Only patients with urge incontinence were included in the study. Patients were evaluated for QOL, anxiety, depression, disability, and geriatric syndromes before and after treatment. Data analysis was done by using SPSS version 22.

RESULTS

The study population was 42 women; the mean age was 69.7 +/- 4.3 years.  QoL, anxiety, and depression symptoms, and ADL were revealed to be improved after treatment. ICIQ-SF, I-QOL, and HADs scores were associated with UI treatment when evaluated with one-way MANOVA (F [4, 79] =3.25, p=0.00, Wilk's Λ=0.859, partial η2=0.14).

CONCLUSION

UI is a common problem in the elderly. Patients usually hesitate to tell this complaint to even doctors. That situation affects their physical and psychological condition negatively. In this study, we reached that anticholinergic treatment (fesoterodine) improved ADL, QoL, and psychological symptoms. Those findings represented us that proper treatment of UI is critical for healthy aging.

摘要

目的

尿失禁(UI)是一个基本的健康问题,可发生于任何年龄,但在老年女性中尤为常见。抑郁和焦虑也是老年人的重要问题。UI 是被认为与抑郁和生活质量(QOL)有关的老年综合征之一。

材料和方法

本前瞻性研究于 2020 年 2 月至 4 月进行了 2 个月。患有 UI 症状的老年女性患者入组本研究。通过使用 3 个失禁问题(3IQ)来确定 UI 的类型。仅纳入急迫性尿失禁患者。在治疗前后评估患者的 QOL、焦虑、抑郁、残疾和老年综合征。使用 SPSS 版本 22 进行数据分析。

结果

研究人群为 42 名女性,平均年龄为 69.7 +/- 4.3 岁。治疗后 QOL、焦虑和抑郁症状以及 ADL 得到改善。用单向 MANOVA 评估时,ICIQ-SF、I-QOL 和 HADs 评分与 UI 治疗相关(F [4, 79] =3.25,p=0.00,Wilk's Λ=0.859,偏η2=0.14)。

结论

UI 在老年人中很常见。患者通常不愿向医生诉说这种抱怨。这种情况会对他们的身体和心理健康产生负面影响。在这项研究中,我们发现抗胆碱能治疗(非索罗定)改善了 ADL、QOL 和心理症状。这些发现表明,对 UI 进行适当的治疗对于健康老龄化至关重要。

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