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ACL 损伤后延迟重建超过 6 个月会影响临床显著结局改善的可能性。

Delaying ACL reconstruction beyond 6 months from injury impacts likelihood for clinically significant outcome improvement.

机构信息

Midwest Orthopaedics at Rush, Rush University Medical Center, Chicago, IL, USA.

Dept. of Orthopaedic Surgery, Mayo Clinic, Rochester, MN, USA.

出版信息

Knee. 2021 Dec;33:290-297. doi: 10.1016/j.knee.2021.10.010. Epub 2021 Oct 30.

DOI:10.1016/j.knee.2021.10.010
PMID:34739960
Abstract

BACKGROUND

The effect of surgical latency on outcomes of anterior cruciate ligament reconstruction (ACLR) is a topic that is heavily debated. Some studies report increased benefit when time from injury to surgery is decreased while other studies report no benefit. The purpose of our analysis was to compare achievement of clinically significant outcomes (CSOs) in patients with greater than six months of time from injury to ACLR to those with less than or equal to six months of time to surgery.

METHODS

Patients undergoing primary ACLR between January 2017 and January 2018 with minimum one year follow-up were included. International Knee Documentation Committee (IKDC) score and Knee Injury and Osteoarthritis Outcomes Score (KOOS) were collected. Multivariate logistic regression was performed for outcome achievement and risk of revision ACLR and Weibull parametric survival analysis was performed for relative time to outcome achievement. The level of significance was set at α = 0.05.

RESULTS

379 patients were included of which, 140 patients sustained ACL injury greater than six months prior to surgery. This group of patients experienced reduced likelihood to achieve patient-acceptable symptomatic state (PASS) on the IKDC (p = 0.03), KOOS Pain (p = 0.01) and a greater likelihood to undergo revision ACLR (p = 0.001). There was no impact of surgical timing on minimal clinically important difference (MCID).

CONCLUSION

Patients with greater than 6 months from injury to ACLR reported reduced likelihood to achieve CSOs, delayed achievement of CSOs, and increased rates of revision surgery.

摘要

背景

手术延迟对前交叉韧带重建(ACLR)结果的影响是一个备受争议的话题。一些研究报告称,受伤后至手术的时间缩短会带来更大的益处,而其他研究则报告称没有益处。我们分析的目的是比较受伤后至 ACLR 的时间大于 6 个月的患者与时间小于或等于 6 个月的患者在达到临床显著结果(CSO)方面的差异。

方法

纳入 2017 年 1 月至 2018 年 1 月期间接受初次 ACLR 且随访时间至少 1 年的患者。收集国际膝关节文献委员会(IKDC)评分和膝关节损伤和骨关节炎结果评分(KOOS)。采用多变量逻辑回归分析结果的获得和 ACLR 翻修的风险,采用威布尔参数生存分析评估达到结果的相对时间。显著性水平设为 α=0.05。

结果

共纳入 379 例患者,其中 140 例患者在手术前 ACL 损伤时间超过 6 个月。这组患者在 IKDC 的患者可接受的症状状态(PASS)(p=0.03)、KOOS 疼痛(p=0.01)和更有可能接受 ACLR 翻修(p=0.001)方面的可能性较小。手术时机对最小临床重要差异(MCID)没有影响。

结论

受伤后至 ACLR 的时间大于 6 个月的患者报告称,他们达到 CSO 的可能性较小,达到 CSO 的时间延迟,以及翻修手术的发生率增加。

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