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站立位 T1-L1 骨盆角:成人脊柱畸形中近端交界性后凸的一种有用的影像学预测指标。

The standing T1-L1 pelvic angle: a useful radiographic predictor of proximal junctional kyphosis in adult spinal deformity.

机构信息

1Department of Spine and Orthopedic Surgery, Japanese Red Cross Medical Center, Tokyo; and.

2Department of Orthopedic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

出版信息

J Neurosurg Spine. 2021 Nov 5;36(4):609-615. doi: 10.3171/2021.7.SPINE21571. Print 2022 Apr 1.

Abstract

OBJECTIVE

Proximal junctional kyphosis (PJK), which can worsen a patient's quality of life, is a common complication following the surgical treatment of adult spinal deformity (ASD). Although various radiographic parameters have been proposed to predict the occurrence of PJK, the optimal method has not been established. The present study aimed to investigate the usefulness of the T1-L1 pelvic angle in the standing position (standing TLPA) for predicting the occurrence of PJK.

METHODS

The authors retrospectively extracted data for patients with ASD who underwent minimum 5-level fusion to the pelvis with upper instrumented vertebra between T8 and L1. In the present study, PJK was defined as ≥ 10° progression of the proximal junctional angle or reoperation due to progressive kyphosis during 1 year of follow-up. The following parameters were analyzed on whole-spine standing radiographs: the T1-pelvic angle, conventional thoracic kyphosis (TK; T4-12), whole-thoracic TK (T1-12), and the standing TLPA (defined as the angle formed by lines extending from the center of T1 and L1 to the femoral head axis). A logistic regression analysis and a receiver operating characteristic curve analysis were performed.

RESULTS

A total of 50 patients with ASD were enrolled (84% female; mean age 74.4 years). PJK occurred in 19 (38%) patients. Preoperatively, the PJK group showed significantly greater T1-pelvic angle (49.2° vs 34.4°), conventional TK (26.6° vs 17.6°), and standing-TLPA (30.0° vs 14.9°) values in comparison to the non-PJK group. There was no significant difference in the whole-thoracic TK between the two groups. A multivariate analysis showed that the standing TLPA and whole-thoracic TK were independent predictors of PJK. The standing TLPA had better accuracy than whole-thoracic TK (AUC 0.86 vs 0.64, p = 0.03). The optimal cutoff value of the standing TLPA was 23.0° (sensitivity 0.79, specificity 0.74). Using this cutoff value, the standing TLPA was the best predictor of PJK (OR 8.4, 95% CI 1.8-39, p = 0.007).

CONCLUSIONS

The preoperative standing TLPA was more closely associated with the occurrence of PJK than other radiographic parameters. These results suggest that this easily measured parameter is useful for the prediction of PJK.

摘要

目的

近端交界性后凸(PJK)可降低患者生活质量,是成人脊柱畸形(ASD)术后的常见并发症。虽然已经提出了多种放射学参数来预测 PJK 的发生,但尚未确定最佳方法。本研究旨在探讨站立位 T1 至 L1 骨盆角(站立 TLPA)在预测 PJK 中的作用。

方法

作者回顾性提取了接受 T8 至 L1 节段以上固定融合至骨盆的 ASD 患者数据。本研究中,PJK 定义为近端交界角增加≥10°或随访 1 年内因进行性后凸而再次手术。在全脊柱站立位 X 线片上分析以下参数:T1 骨盆角、传统胸椎后凸角(TK;T4-12)、全胸椎 TK(T1-12)和站立 TLPA(定义为从 T1 和 L1 中心向股骨头轴线延伸的线形成的角度)。进行逻辑回归分析和受试者工作特征曲线分析。

结果

共纳入 50 例 ASD 患者(84%为女性;平均年龄 74.4 岁)。19 例(38%)患者发生 PJK。术前,PJK 组 T1 骨盆角(49.2°比 34.4°)、传统 TK(26.6°比 17.6°)和站立 TLPA(30.0°比 14.9°)显著更大。两组间全胸椎 TK 无显著差异。多变量分析显示,站立 TLPA 和全胸椎 TK 是 PJK 的独立预测因素。站立 TLPA 的准确性优于全胸椎 TK(AUC 0.86 比 0.64,p=0.03)。站立 TLPA 的最佳截断值为 23.0°(敏感性 0.79,特异性 0.74)。使用该截断值,站立 TLPA 是 PJK 的最佳预测因素(OR 8.4,95%CI 1.8-39,p=0.007)。

结论

术前站立 TLPA 与 PJK 的发生关系更为密切,优于其他放射学参数。这些结果表明,该易于测量的参数可用于 PJK 的预测。

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