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英国一家托儿所爆发的 2019 年冠状病毒病。

Outbreak of SARS-CoV-2 in a Children's Nursery in the United Kingdom.

机构信息

From the Public Health Department, Cambridgeshire County Council.

Early Years Service, Cambridgeshire County Council.

出版信息

Pediatr Infect Dis J. 2021 Dec 1;40(12):e455-e458. doi: 10.1097/INF.0000000000003362.

DOI:10.1097/INF.0000000000003362
PMID:34740997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8575081/
Abstract

BACKGROUND

Early Years' Settings (EYSs) provide childcare and education for children 0-5 years old. They remained fully open in England during the third National lockdown when other educational settings were only open for selected children. EYSs are generally considered to be low-risk settings for transmission of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2).

METHODS

An observational study describing a large outbreak of SARS CoV-2 within an EYS in Cambridgeshire, United Kingdom.

RESULTS

Overall 45 cases of SARS-CoV-2 were identified; 24 adults (71% of staff members) and 21 children (25% of nursery attendees). One case was identified as the alpha variant (B.1.1.7 [VOC-20-DEC-01]). One staff member became critically unwell.

CONCLUSIONS

Transmission of SARS-CoV-2 occurred quickly, with a high attack rate; likely a consequence of a variant with enhanced transmissibility and an inability of the setting to adhere to infection control measures.

摘要

背景

早期教育环境(EYS)为 0-5 岁儿童提供儿童保育和教育。在英格兰第三次全国封锁期间,其他教育环境仅对部分儿童开放,而 EYS 则保持全面开放。通常认为 EYS 是传播严重急性呼吸系统综合症冠状病毒 2(SARS-CoV-2)的低风险环境。

方法

一项描述在英国剑桥郡的一所 EYS 中 SARS-CoV-2 大规模爆发的观察性研究。

结果

共发现 45 例 SARS-CoV-2 病例;24 名成年人(占员工的 71%)和 21 名儿童(占托儿所出勤率的 25%)。1 例被确定为 alpha 变体(B.1.1.7 [VOC-20-DEC-01])。1 名工作人员病情严重。

结论

SARS-CoV-2 传播迅速,发病率高;可能是由于具有更高传染性的变体以及该环境无法遵守感染控制措施所致。

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本文引用的文献

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SARS-CoV-2 infection and transmission in educational settings: a prospective, cross-sectional analysis of infection clusters and outbreaks in England.SARS-CoV-2 感染与传播在教育环境中的情况:对英格兰感染集群和疫情的前瞻性、横断面分析。
Lancet Infect Dis. 2021 Mar;21(3):344-353. doi: 10.1016/S1473-3099(20)30882-3. Epub 2020 Dec 8.
2
Stepwise School Opening and an Impact on the Epidemiology of COVID-19 in the Children.分阶段开学与 COVID-19 在儿童中的流行病学影响
J Korean Med Sci. 2020 Nov 30;35(46):e414. doi: 10.3346/jkms.2020.35.e414.
3
Transmission of SARS-CoV-2 in children aged 0 to 19 years in childcare facilities and schools after their reopening in May 2020, Baden-Württemberg, Germany.2020 年 5 月重新开放后,德国巴登-符腾堡州托幼机构和学校中 0 至 19 岁儿童的 SARS-CoV-2 传播。
Euro Surveill. 2020 Sep;25(36). doi: 10.2807/1560-7917.ES.2020.25.36.2001587.
4
Transmission of SARS-CoV-2 in Australian educational settings: a prospective cohort study.澳大利亚教育环境中 SARS-CoV-2 的传播:一项前瞻性队列研究。
Lancet Child Adolesc Health. 2020 Nov;4(11):807-816. doi: 10.1016/S2352-4642(20)30251-0. Epub 2020 Aug 3.
5
Novel Coronavirus 2019 Transmission Risk in Educational Settings.2019 年新型冠状病毒在教育环境中的传播风险。
Clin Infect Dis. 2021 Mar 15;72(6):1055-1058. doi: 10.1093/cid/ciaa794.
6
No evidence of secondary transmission of COVID-19 from children attending school in Ireland, 2020.没有证据表明 2020 年在爱尔兰上学的儿童会二次传播 COVID-19。
Euro Surveill. 2020 May;25(21). doi: 10.2807/1560-7917.ES.2020.25.21.2000903.