Ellis G L, Lewis D M, Carleton A S
J Am Dent Assoc. 1987 May;114(5):678-80. doi: 10.14219/jada.archive.1987.0145.
Florid osseous dysplasia is a peculiar reactive or developmental bone disease that is known to appear only in the jaws. It has an inexplicable decided predilection for occurrence in middle-aged, black women. Extent of the disease may vary from a few isolated periapical lesions to diffuse involvement of the mandibular and maxillary alveolar processes. Radiographically, it is characterized by multiquadrant, globular, radiolucent-radiopaque lesions. Histopathologically, it is a benign fibro-osseous lesion that must be differentiated from other benign fibro-osseous lesions such as fibrous dysplasia, ossifying fibroma, Paget's disease, and sclerosing osteomyelitis on the basis of combined clinical, radiographic, and histological features. Correctly identifying this disease is important because it requires no treatment unless a secondary osteomyelitis develops. Sequestrae and osteomyelitis are complications arising when teeth are removed and removable dental prostheses are supported by diseased bone.
florid骨发育异常是一种特殊的反应性或发育性骨病,已知仅发生于颌骨。它对中年黑人女性有无法解释的明显偏好。疾病范围可从少数孤立的根尖周病变到下颌和上颌牙槽突的弥漫性受累。影像学上,其特征为多象限、球形、透射线-阻射线混合的病变。组织病理学上,它是一种良性纤维-骨病变,必须根据临床、影像学和组织学特征相结合,与其他良性纤维-骨病变如骨纤维异常增殖症、骨化性纤维瘤、佩吉特病和硬化性骨髓炎相鉴别。正确识别这种疾病很重要,因为除非发生继发性骨髓炎,否则无需治疗。死骨和骨髓炎是拔牙以及可摘义齿由患病骨支持时出现的并发症。