School of Human and Behavioural Sciences, Bangor University, Bangor, Gwynedd, Wales, LL57 2AS, United Kingdom.
School of Human and Behavioural Sciences, Bangor University, Bangor, Gwynedd, Wales, LL57 2AS, United Kingdom.
Neuroimage. 2021 Dec 15;245:118702. doi: 10.1016/j.neuroimage.2021.118702. Epub 2021 Nov 4.
The contribution and neural basis of cognitive control is under-specified in many prominent models of socio-cognitive processing. Important outstanding questions include whether there are multiple, distinguishable systems underpinning control and whether control is ubiquitously or selectively engaged across different social behaviours and task demands. Recently, it has been proposed that the regulation of social behaviours could rely on brain regions specialised in the controlled retrieval of semantic information, namely the anterior inferior frontal gyrus (IFG) and posterior middle temporal gyrus. Accordingly, we investigated for the first time whether the neural activation commonly found in social functional neuroimaging studies extends to these 'semantic control' regions. We conducted five coordinate-based meta-analyses to combine results of 499 fMRI/PET experiments and identified the brain regions consistently involved in semantic control, as well as four social abilities: theory of mind, trait inference, empathy and moral reasoning. This allowed an unprecedented parallel review of the neural networks associated with each of these cognitive domains. The results confirmed that the anterior left IFG region involved in semantic control is reliably engaged in all four social domains. This supports the hypothesis that social cognition is partly regulated by the neurocognitive system underpinning semantic control.
在许多著名的社会认知加工模型中，认知控制的贡献和神经基础都没有得到明确说明。重要的悬而未决的问题包括是否存在多个可区分的系统来支持控制，以及控制是否普遍或选择性地参与不同的社会行为和任务需求。最近，有人提出，社会行为的调节可能依赖于大脑中专门用于控制语义信息检索的区域，即前下额回（IFG）和后颞中回。因此，我们首次调查了社会功能神经影像学研究中常见的神经激活是否扩展到这些“语义控制”区域。我们进行了五次基于坐标的荟萃分析，合并了 499 项 fMRI/PET 实验的结果，确定了与语义控制以及四种社会能力相关的一致涉及的大脑区域：心理理论、特质推理、同理心和道德推理。这使得对与这些认知领域相关的神经网络进行了前所未有的平行审查。结果证实，参与语义控制的左侧前 IFG 区域确实与所有四个社会领域都有关联。这支持了这样一种假设，即社会认知部分受到支持语义控制的神经认知系统的调节。
