UTMB School of Medicine, Galveston, TX.
Pediatr Emerg Care. 2022 Mar 1;38(3):133-135. doi: 10.1097/PEC.0000000000002564.
Staphylococcal scalded skin syndrome is a superficial blistering disorder caused by exfoliative toxin-releasing strains of Staphylococcus aureus. Bacterial toxins are released hematogenously, and after a prodromal fever and exquisite tenderness of skin, patients present with tender erythroderma and flaccid bullae with subsequent superficial generalized exfoliation. The head-to-toe directed exfoliation lasts up to 10 to 14 days without scarring after proper treatment. Children younger than 6 years are predominantly affected because of their lack of toxin-neutralizing antibodies and the immature renal system's inability to excrete the causative exotoxins. The epidemiology, pathophysiology, and essential primary skin lesions used to diagnose staphylococcal scalded skin syndrome are summarized for the pediatric emergency medicine physician.
葡萄球菌性烫伤样皮肤综合征是一种由表皮松解毒素释放型金黄色葡萄球菌引起的浅表性水疱病。细菌毒素经血液释放，在出现前驱发热和皮肤极度敏感后，患者出现触痛性红斑和松弛性大疱，随后出现广泛的浅表性剥脱。在适当治疗后，从头到脚的剥脱可持续 10 至 14 天，无瘢痕。由于儿童缺乏中和毒素的抗体，以及其不成熟的肾脏系统无法排出致病外毒素，6 岁以下的儿童是主要发病群体。本文总结了葡萄球菌性烫伤样皮肤综合征的流行病学、病理生理学和基本皮肤损害，旨在为儿科急诊医师提供相关信息。
