University of Florida College of Medicine, Gainesville, FL 32610, USA.
Department of Dermatology, University of Florida College of Medicine, Gainesville, FL 32610, USA.
Medicina (Kaunas). 2021 Oct 24;57(11):1157. doi: 10.3390/medicina57111157.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by . The pathogenesis of both conditions centers around exotoxin mediated cleavage of desmoglein-1, which results in intraepidermal desquamation. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target These conditions can sometimes be confused with other conditions that result in superficial blistering; the distinguishing features are outlined below.
葡萄球菌性烫伤样皮肤综合征 (SSSS) 和大疱性脓疱疮是由 引起的感染。这两种疾病的发病机制都围绕着外毒素介导的桥粒芯糖蛋白-1 的裂解，导致表皮内剥脱。大疱性脓疱疮是由于这些毒素的局部释放，因此，通常表现为局部皮肤发现，而 SSSS 是由于这些毒素的全身扩散，导致更广泛的皮疹和严重的表现。这两种情况都用抗生素治疗，这些抗生素针对 这些疾病有时可能与其他导致浅表性水疱的疾病混淆；下面列出了它们的鉴别特征。
