全膝关节置换术在不同程度遵循多模式疼痛管理方案下的术后结果。
Postoperative outcomes of total knee arthroplasty across varying levels of multimodal pain management protocol adherence.
作者信息
Harrison Anna E, Kozarek Jason D B, Yeh Justin, MacDonald James H, Ruiz-Pelaez Juan G, Barengo Noël C, Turcotte Justin J, King Paul J
机构信息
Florida International University, Herbert Wertheim College of Medicine, Miami, FL, USA.
Luminis Health Anne Arundel Medical Center, Annapolis, MD, USA.
出版信息
J Orthop. 2021 Oct 13;28:26-33. doi: 10.1016/j.jor.2021.10.005. eCollection 2021 Nov-Dec.
Abstract
We examined the effect of varying multimodal pain management (MMPM) combinations on oral morphine milligram equivalents (OMME) and length of stay (LOS) after total knee arthroplasty (TKA). Five groups were compared based on the combination of multimodal analgesics ranging from no MMPM to full MMPM with acetaminophen, gabapentinoids, and celecoxib. After risk adjustment, MMPM was associated with decreased odds of LOS ≥2 days and OMME ≥75th percentile. MMPM protocols are effective at reducing LOS and postoperative narcotic requirements post-TKA. Patients appear to derive similar benefit from receiving all three medications, as well as various combinations of these drugs.
摘要
我们研究了不同的多模式疼痛管理（MMPM）组合对全膝关节置换术（TKA）后口服吗啡毫克当量（OMME）和住院时间（LOS）的影响。根据多模式镇痛药的组合，将五组进行了比较，范围从不使用MMPM到使用对乙酰氨基酚、加巴喷丁类药物和塞来昔布的完全MMPM。在进行风险调整后，MMPM与LOS≥2天和OMME≥第75百分位数的几率降低相关。MMPM方案在减少TKA后的LOS和术后麻醉剂需求方面是有效的。患者似乎从接受所有三种药物以及这些药物的各种组合中获得了相似的益处。
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