白细胞破碎性血管炎导致阴茎坏死及膀胱和尿道缺血。
Leukocytoclastic vasculitis leading to penile necrosis and ischemia of the bladder and urethra.
作者信息
Moseley Isabelle, Greenberg Rachel, Wasserman Meredith, Thavaseelan Simone, Cancian Madeline
机构信息
Warren Alpert Medical School, Brown University, Providence, RI, 02903, USA.
Department of Urology, Warren Alpert Medical School, Brown University, RI, 02903, USA.
出版信息
Urol Case Rep. 2021 Oct 19;40:101902. doi: 10.1016/j.eucr.2021.101902. eCollection 2022 Jan.
We report a case of leukocytoclastic vasculitis-induced penile necrosis in a 69-year-old male with no previous urologic history. After suffering an ischemic event to the distal shaft of the penis as well as an ischemic event involving the right side of the bladder, he underwent suprapubic tube placement for urinary diversion. Despite attempts at anticoagulation for penile salvage, he lost the distal aspect of the glans penis to auto-necrosis. Ultimately, the underlying disease was determined to be systemic ANCA-associated vasculitis, and the patient was treated with rituximab and prednisone as well as penile wound debridement.
我们报告一例69岁男性白细胞破碎性血管炎所致阴茎坏死病例，该患者既往无泌尿外科病史。阴茎远端干段及膀胱右侧发生缺血事件后，他接受了耻骨上造瘘管置入术以进行尿液改道。尽管尝试抗凝以挽救阴茎，但他仍因自身坏死失去了阴茎头的远端部分。最终，确定潜在疾病为系统性抗中性粒细胞胞浆抗体相关性血管炎，患者接受了利妥昔单抗、泼尼松治疗以及阴茎伤口清创术。
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