白血病患者人骨髓中含免疫球蛋白细胞的分布
Distribution of immunoglobulin containing cells in human bone marrow of patients with leukemia.
作者信息
Suzuki K, Hirokawa K, Kamiyama R, Hatakeyama S
出版信息
Acta Pathol Jpn. 1987 Feb;37(2):193-9. doi: 10.1111/j.1440-1827.1987.tb03054.x.
In the bone marrow of leukemic patients (31 cases), the number of immunoglobulin containing cells per unit square significantly decreased to the level of approximately 20-50% of the age-matched control, although the serum level of immunoglobulin in these patients was almost comparable to the control level. The number of immunoglobulin containing cells in the bone marrow was inversely related with the degree of infiltration of leukemic cells and the correlation of Ig-G containing cell count (Y) and percentage of blast cells (X) was Y = 91.8-1.9X (r = -0.436, P less than 0.05). Follow-up examination of the bone marrow after chemotherapy revealed that the recovery of the number of immunoglobulin containing cells in the remission state appeared to occur in younger patients, but not in older ones.
在白血病患者（31例）的骨髓中，每单位面积含免疫球蛋白细胞的数量显著下降至约为年龄匹配对照组水平的20 - 50%，尽管这些患者的血清免疫球蛋白水平与对照组几乎相当。骨髓中含免疫球蛋白细胞的数量与白血病细胞的浸润程度呈负相关，且含Ig - G细胞计数（Y）与原始细胞百分比（X）的相关性为Y = 91.8 - 1.9X（r = - 0.436，P < 0.05）。化疗后对骨髓的随访检查显示，处于缓解状态的含免疫球蛋白细胞数量的恢复在年轻患者中似乎会出现，但老年患者则不然。
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