Plk1 in Asthma: Ready for Primetime?
作者信息
Tam John Kit Chung, Tran Thai
机构信息
Yong Loo Lin School of Medicine National University of Singapore Singapore.
Department of Cardiac, Thoracic, and Vascular Surgery National University Heart Centre Singapore.
出版信息
Am J Respir Cell Mol Biol. 2022 Feb;66(2):124-125. doi: 10.1165/rcmb.2021-0425ED.
Abstract
摘要
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本文引用的文献
1
Plk1 Regulates Caspase-9 Phosphorylation at Ser-196 and Apoptosis of Human Airway Smooth Muscle Cells.Plk1 调节人呼吸道平滑肌细胞 Caspase-9 的丝氨酸 196 位磷酸化和细胞凋亡。
Am J Respir Cell Mol Biol. 2022 Feb;66(2):223-234. doi: 10.1165/rcmb.2021-0192OC.
2
Polo-like Kinase 1 Regulates Vimentin Phosphorylation at Ser-56 and Contraction in Smooth Muscle.Polo样激酶1调节波形蛋白Ser-56位点的磷酸化及平滑肌收缩。
J Biol Chem. 2016 Nov 4;291(45):23693-23703. doi: 10.1074/jbc.M116.749341. Epub 2016 Sep 23.
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Plk1 Inhibitors in Cancer Therapy: From Laboratory to Clinics.Plk1抑制剂在癌症治疗中的应用：从实验室到临床
Mol Cancer Ther. 2016 Jul;15(7):1427-35. doi: 10.1158/1535-7163.MCT-15-0897. Epub 2016 Jun 21.
4
Plk1 regulates MEK1/2 and proliferation in airway smooth muscle cells.Polo样激酶1（Plk1）调节气道平滑肌细胞中的丝裂原活化蛋白激酶激酶1/2（MEK1/2）和细胞增殖。
Respir Res. 2015 Aug 5;16(1):93. doi: 10.1186/s12931-015-0257-8.
5
Laminin drives survival signals to promote a contractile smooth muscle phenotype and airway hyperreactivity.层粘连蛋白驱动存活信号促进收缩性平滑肌表型和气道高反应性。
FASEB J. 2013 Oct;27(10):3991-4003. doi: 10.1096/fj.12-221341. Epub 2013 Jun 11.
6
Polo-like kinase 1 is essential for early embryonic development and tumor suppression.Polo样激酶1对早期胚胎发育和肿瘤抑制至关重要。
Mol Cell Biol. 2008 Nov;28(22):6870-6. doi: 10.1128/MCB.00392-08. Epub 2008 Sep 15.
7
Polo-like kinase 1 is involved in invasion through extracellular matrix.Polo样激酶1参与通过细胞外基质的侵袭过程。
Cancer Res. 2007 Dec 1;67(23):11106-10. doi: 10.1158/0008-5472.CAN-07-2348.
8
Airway smooth muscle phenotype and function: interactions with current asthma therapies.气道平滑肌表型与功能：与当前哮喘治疗方法的相互作用
Curr Drug Targets. 2006 May;7(5):525-40. doi: 10.2174/138945006776818728.
9
Targeting polo-like kinase 1 for cancer therapy.靶向Polo样激酶1用于癌症治疗。
Nat Rev Cancer. 2006 Apr;6(4):321-30. doi: 10.1038/nrc1841.
10
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Prog Cell Cycle Res. 1996;2:107-14. doi: 10.1007/978-1-4615-5873-6_11.
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