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保留生育功能治疗疑似平滑肌肉瘤:行经宫颈子宫肌瘤活组织检查避免子宫切除术。

Fertility-sparing management of a suspicion of leiomyosarcoma: avoiding hysterectomy by performing transcervical myoma biopsy.

机构信息

Department of Obstetrics and Gynecology, Montpellier University Hospital, Montpellier, France.

Department of Radiology, Montpellier University Hospital, Montpellier, France.

出版信息

Fertil Steril. 2022 Jan;117(1):230-231. doi: 10.1016/j.fertnstert.2021.09.028. Epub 2021 Nov 6.

DOI:10.1016/j.fertnstert.2021.09.028
PMID:34753598
Abstract

OBJECTIVE

To describe the fertility-sparing management of an atypical uterine myoma.

DESIGN

Step-by-step video explanation of transcervical biopsy using transabdominal ultrasound guidance, highlighting tips and tricks. Patient consent was obtained before the publication of the case.

SETTING

University hospital.

PATIENT(S): A 32-year-old nulliparous woman with a history of dysmenorrhea was found to have an atypical myoma FIGO 6, with suspicion of leiomyosarcoma on magnetic resonance imaging.

INTERVENTION(S): A transcervical biopsy of an atypical myoma was done under transabdominal ultrasound guidance. A myomectomy by a minimally invasive approach was performed without morcellation.

MAIN OUTCOME MEASURE(S): Feasibility of transcervical biopsy and correlation with definitive anatomopathological diagnosis.

RESULT(S): The patient was under general anesthesia. A hysteroscopy confirmed the normal appearance of the uterine cavity with no direct access to the myoma. Four core biopsies were performed with a 16-gauge needle transcervically under ultrasound guidance. The preliminary diagnosis of cellular leiomyoma allowed a fertility-sparing surgery. Myomectomy and surgical treatment of endometriosis were performed secondarily. This patient had a successful recovery, and the diagnosis of benign cellular leiomyoma was confirmed on the surgical specimen.

CONCLUSION(S): The current video highlights the safety and feasibility of transcervical ultrasound-guided core biopsy in patients with atypical uterine fibroids.

摘要

目的

描述非典型子宫肌瘤的保留生育力管理。

设计

经腹超声引导下经宫颈活检的分步视频讲解,突出技巧和窍门。在发表该病例之前获得了患者的同意。

地点

大学医院。

患者

一名 32 岁的初产妇,有痛经史,磁共振成像怀疑为非典型子宫肌瘤 FIGO 6,伴平滑肌肉瘤。

干预

经腹超声引导下对非典型子宫肌瘤进行经宫颈活检。通过微创方法进行子宫肌瘤切除术,不进行分碎。

主要观察指标

经宫颈活检的可行性及与明确解剖病理学诊断的相关性。

结果

患者接受全身麻醉。宫腔镜检查证实子宫腔外观正常,无法直接触及肌瘤。在超声引导下经宫颈用 16 号针进行了 4 次核心活检。初步诊断为细胞性平滑肌瘤,允许保留生育力的手术。随后进行子宫肌瘤切除术和子宫内膜异位症的手术治疗。该患者恢复良好,手术标本诊断为良性细胞性平滑肌瘤。

结论

本视频重点介绍了经腹超声引导下经宫颈核心活检在非典型子宫纤维瘤患者中的安全性和可行性。

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