一名患有与多发性骨髓瘤相关的血栓形成倾向的患者，其血栓形成的脑动静脉畸形自发消退：病例报告及文献综述
Spontaneous regression of a thrombosed cerebral arteriovenous malformation in a patient with a prothrombotic state associated with multiple myeloma: A case report and literature review.
作者信息
Arenas-Ruiz José A, Hernández-Álvarez Nickjail, de Llano Juan P Navarro-Garcia, Ponce-Ayala Aurelio, Nathal Edgar
机构信息
Department of Neurosurgery, Hospital Universitario "Dr. José Eleuterio González" UANL, Monterrey, Nuevo León.
Department of Neurosurgery, Instituto Nacional de Neurología y Neurocirugía, Ciudad de México, Mexico.
出版信息
Surg Neurol Int. 2021 Oct 19;12:521. doi: 10.25259/SNI_666_2021. eCollection 2021.
BACKGROUND
Cerebral arteriovenous malformations (AVMs) are pathologic communications between veins and arteries of the brain vasculature. Its spontaneous regression is rare, and many factors have been described in the effort to explain this phenomenon, including a hypercoagulable state.
CASE DESCRIPTION
We present the case of a spontaneous unruptured AVM regression in a patient where thrombosis of the malformation was found, probably due to a prothrombotic state associated with multiple myeloma (MM).
CONCLUSION
We aim to contribute to the study of this rare phenomenon, presenting the relationship between a hypercoagulable state caused by MM and the spontaneous AVM regression that has not been previously reported.
背景
脑动静脉畸形（AVM）是脑血管系统中静脉与动脉之间的病理性交通。其自发消退极为罕见，为解释这一现象已描述了许多因素，包括高凝状态。
病例描述
我们报告了一例脑动静脉畸形自发未破裂消退的病例，该病例中发现畸形发生血栓形成，可能是由于与多发性骨髓瘤（MM）相关的血栓前状态所致。
结论
我们旨在为这一罕见现象的研究做出贡献，阐述多发性骨髓瘤所致高凝状态与此前未报道的脑动静脉畸形自发消退之间的关系。
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