Shahidatul-Adha Mohamad, Saizul Zubaidah, Hussain Faezahtul-Arbaeyah, Abdullah Baharudin
Department of Ophthalmology & Visual Science, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.
Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.
Cureus. 2021 Oct 6;13(10):e18548. doi: 10.7759/cureus.18548. eCollection 2021 Oct.
Rhabdomyosarcoma (RMS) is the most common soft-tissue tumor in children, frequently affecting the nose, nasopharynx, and paranasal sinuses. RMS of this sinonasal region manifests with non-specific nasal symptoms of allergic rhinitis, sinusitis, or upper airway infection. Associated ocular symptoms are rare. We describe a young girl who presented with acute onset squint secondary to sinonasal RMS. Imaging showed an aggressive sinonasal tumor with oropharyngeal, intraorbital, and intracranial extension. Histopathological findings were consistent with a diagnosis of rhabdomyosarcoma, embryonal type. The patient deteriorated rapidly due to disease complications. We provide a literature review of pediatric sinonasal RMS with various manifestations.
横纹肌肉瘤（RMS）是儿童最常见的软组织肿瘤，常累及鼻、鼻咽和鼻窦。鼻窦区域的RMS表现为过敏性鼻炎、鼻窦炎或上呼吸道感染等非特异性鼻部症状。相关的眼部症状罕见。我们描述了一名年轻女孩，她因鼻窦RMS继发急性斜视就诊。影像学检查显示鼻窦有侵袭性肿瘤，累及口咽、眶内和颅内。组织病理学检查结果符合胚胎型横纹肌肉瘤的诊断。患者因疾病并发症迅速恶化。我们对小儿鼻窦RMS的各种表现进行了文献综述。
