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预防性峡部消融治疗心房颤动时房扑发生率和三尖瓣峡部再传导的临床研究、综述,并与既往研究结果比较。

Rates of atrial flutter occurrence and cavotricuspid isthmus reconduction after prophylactic isthmus ablation performed during atrial fibrillation ablation: a clinical study, review, and comparison with previous findings.

机构信息

Heart Rhythm Center, Okayama Heart Clinic, Takeda 54-1, Naka-Ku, Okayama, 703-8251, Japan.

Department of Medical Technology, Okayama University Graduate School of Health Okayama, Japan Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.

出版信息

J Interv Card Electrophysiol. 2022 Jun;64(1):67-76. doi: 10.1007/s10840-021-01087-8. Epub 2021 Nov 9.

DOI:10.1007/s10840-021-01087-8
PMID:34755243
Abstract

PURPOSE

Based on the high rate of coexisting atrial fibrillation (AF) and atrial flutter (AFL), prophylactic cavotricuspid isthmus ablation (CTIA) adjunctive to AF ablation has recently been attempted in patients with AF and without AFL. The present study aimed to determine the rates of AFL occurrence and CTI reconduction after performing CTI ablation adjunctive to AF ablation.

METHODS

We analyzed the data of 3833 consecutive patients with AF, who underwent prophylactic CTIA with AF ablation between 2009 and 2020.

RESULTS

In all patients, CTIA and AF ablations were successful. Clinical AFL occurred in seven patients (0.18%, 7/3,833), and the observed rate was lower than those reported for cases of AF ablation without CTIA and for those of CTIA for pure AFL. A second ablation was needed in 745 patients at a median of 253 days (25 and 75 percentiles, 116 and 775 days) after the first ablation. In 12.1% (90/745) of the patients, CTI reconduction was observed. The reconduction rate was lower than that previously reported for CTIA for pure AFL.

CONCLUSIONS

The present retrospective study found acceptably low rates of clinical AFL occurrence and CTI reconduction following prophylactic CTIA performed with AF ablation, which was supported by the findings obtained after performing a comparison of the rates with those of other ablations (AF ablation only and CTIA for pure AFL). Considering the high correlation between AF and AFL, the present study provided information regarding the efficacy of adjunctive CTIA.

摘要

目的

鉴于房性颤动(AF)和房性扑动(AFL)共存率较高,最近尝试在无 AFL 的 AF 患者中进行 AF 消融联合预防性三尖瓣峡部消融(CTIA)。本研究旨在确定在进行 AF 消融联合 CTIA 后,AFL 发生和 CTI 再传导的发生率。

方法

我们分析了 2009 年至 2020 年间连续 3833 例接受 AF 预防性 CTIA 联合 AF 消融的患者数据。

结果

所有患者的 CTIA 和 AF 消融均成功。7 例(0.18%,7/3833)出现临床 AFL,观察到的发生率低于未行 CTIA 的 AF 消融和单纯 AFL 的 CTIA 报告的发生率。745 例患者在第一次消融后中位数 253 天(25 和 75 百分位数,116 和 775 天)需要再次消融。在 12.1%(90/745)的患者中观察到 CTI 再传导。再传导率低于单纯 AFL 的 CTIA 报告的再传导率。

结论

本回顾性研究发现,在进行 AF 消融联合预防性 CTIA 后,临床 AFL 发生和 CTI 再传导的发生率可接受较低,这与其他消融(仅 AF 消融和单纯 AFL 的 CTIA)的发生率比较结果一致。考虑到 AF 和 AFL 之间的高度相关性,本研究提供了关于联合 CTIA 疗效的信息。

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