ETH Zürich, Institute of Integrative Biology (IBZ), Universitätsstrasse 16, CH-8092 Zürich, Switzerland.
Curr Opin Insect Sci. 2022 Feb;49:31-36. doi: 10.1016/j.cois.2021.10.005. Epub 2021 Oct 29.
A useful discussion of defence strategies cannot do without linking defence mechanisms to their function, that is, their contributions to fitness. Whereas the former is the domain of immunology, the latter is the subject of evolutionary ecology. For this, the concepts of the defence chart and the disease space can be used to connect the two domains and to sharpen the focus. These use different approaches but converge to the same end, that is, to understand what fitness costs and benefits are associated with existing mechanisms and how to identify the best defence strategy in a given environment.
对防御策略的有益讨论离不开将防御机制与其功能（即对适合度的贡献）联系起来。前者是免疫学的领域，后者是进化生态学的主题。为此，可以使用防御图表和疾病空间的概念将这两个领域联系起来，并使重点更加突出。这些概念使用不同的方法，但都趋向于同一个目的，即了解与现有机制相关的适应值成本和收益，以及如何在特定环境中确定最佳防御策略。
