Zhang Xinyue, Fang Weilan, Zeng Liangtao, Liu Fanrong
Department of Pathology, The Second Affiliated Hospital of Nanchang University Nanchang, China.
Int J Clin Exp Pathol. 2021 Oct 15;14(10):1065-1068. eCollection 2021.
Solitary necrotic nodule of the liver (SNNL) is an uncommon disease in clinical practice, and its pathogenesis is still unclear. Here, we report the case of a 35-year-old woman. After physical examination, the patient was found to have a liver neoplasm, and there were no other physical complaints. Abdominal contrast-enhanced computed tomography (CT) showed the presence of a hypodense lesion. The patient opted for surgery to eliminate the lesion. Pathologic examination revealed an isolated necrotic nodular lesion with a size of 12 cm×10 cm×10 cm. The patient had a history of hepatitis B infection. To our knowledge, this is the largest SNNL ever reported and the first case with a history of hepatitis B infection.
肝脏孤立性坏死结节（SNNL）在临床实践中是一种罕见疾病，其发病机制仍不清楚。在此，我们报告一例35岁女性病例。体格检查发现该患者患有肝脏肿瘤，且无其他身体不适主诉。腹部增强计算机断层扫描（CT）显示存在一个低密度病变。患者选择手术切除该病变。病理检查显示为一个孤立的坏死性结节病变，大小为12 cm×10 cm×10 cm。该患者有乙型肝炎感染史。据我们所知，这是迄今为止报道的最大的SNNL病例，也是首例有乙型肝炎感染史的病例。
