Faghih Dinevari Masood, Rasoolimanesh Mehdi, Tarverdizadeh Mehdi, Riazi Ali, Abbasian Samaneh, Zeinolabedini Aysan, Hassannezhad Sina
Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Caspian J Intern Med. 2021;12(Suppl 2):S474-S478. doi: 10.22088/cjim.12.0.474.
Little is known about the development of acute pancreatitis as a complication of corona virus disease of 2019 (COVID-19) infection. This case report describes the presentation of acute pancreatitis in a young woman who then was diagnosed with COVID-19 infection.
An 18-year old previously healthy woman referred to Imam Raza hospital, Tabriz, Iran with a 3-day history of intermittent and crampy abdominal pain. She had serum amylase of 1288 IU/L and serum lipase of 1541 IU/L. She was diagnosed with acute pancreatitis. She was instructed nil per os (NPO) and serum therapy and also was given pantoprazole, and pethidine for her pain management. The laboratory tests for assessing the etiology of acute pancreatitis were normal. Abdominal and pelvic spiral computed tomography (CT) scan revealed edematous pancreas and enhancing loculi fluid accumulation around pancreas along with the small amount of ascites fluid that all suggest acute pancreatitis. Due to the presentation of fever and COVID-19 pandemic and her potential society exposure, we tested SARS CoV-2 by polymerase chain reaction which was positive. The blood C-reactive protein (CRP) level was 3+ but the chest x-ray showed no findings compatible with COVID-19. Eventually after receiving conservative therapy for her pancreatitis, she was discharged from hospital in the good general condition and she has not experienced any episodes of abdominal pain again.
This case highlights acute pancreatitis as a suspected complication associated with COVID-19 and the need for further research.
关于新型冠状病毒肺炎（COVID-19）感染并发症急性胰腺炎的发生情况知之甚少。本病例报告描述了一名年轻女性患急性胰腺炎并随后被诊断为COVID-19感染的情况。
一名18岁既往健康的女性因间歇性痉挛性腹痛3天转诊至伊朗大不里士的伊玛目礼萨医院。她的血清淀粉酶为1288 IU/L，血清脂肪酶为1541 IU/L。她被诊断为急性胰腺炎。医嘱禁食（NPO）并进行血清治疗，还给予泮托拉唑和哌替啶用于止痛。评估急性胰腺炎病因的实验室检查结果正常。腹部和盆腔螺旋计算机断层扫描（CT）显示胰腺水肿，胰腺周围有强化的小房性液体积聚以及少量腹水，均提示急性胰腺炎。由于出现发热以及COVID-19大流行且她有潜在的社交接触史，我们通过聚合酶链反应检测了严重急性呼吸综合征冠状病毒2（SARS-CoV-2），结果呈阳性。血液C反应蛋白（CRP）水平为3+，但胸部X线检查未发现与COVID-19相符的表现。最终，在接受胰腺炎保守治疗后，她以良好的总体状况出院，且未再经历腹痛发作。
本病例突出了急性胰腺炎作为与COVID-19相关的疑似并发症以及进一步研究的必要性。
