Klubien Jeanett, Kohl Andreas P, Nolsøe Christian P, Rosenberg Jacob, Pommergaard Hans-Christian
Center for Perioperative Optimization Department of Surgery Herlev Hospital Herlev Ringvej 75 2730 Herlev Denmark.
Faculty of Health and Medical Sciences University of Copenhagen Blegdamsvej 3B 2200 København N Denmark.
Australas J Ultrasound Med. 2018 Apr 2;21(2):87-95. doi: 10.1002/ajum.12088. eCollection 2018 May.
Liver metastases from colorectal cancer are common and ablation therapy is a favourable treatment option for selected patients not suited for surgical resection. This study aimed to systematically review the literature and present prognostic factors associated with survival and local recurrence after percutaneous ultrasound-guided ablation treatment.
This review is reported according to the PRISMA. PubMed, Embase and Scopus were searched and records were independently screened by two authors, initially on title and abstract and subsequently on full-text basis. The quality of the studies was assessed using the Newcastle-Ottawa quality assessment scale.
Of 2.882 records screened, 18 studies were included. The median survival was 23 months. One-year survival was median 95% and 3-year survival was median 58%. Complete ablation response and adjuvant chemotherapy produce considerably improved survival and low local recurrence rate outcomes.
Percutaneous ultrasound-guided ablation technique for colorectal liver metastases provides impressive survival rates for patients not suited for surgical resection. However, there are some factors related to poorer prognosis, which may be considered when selecting patients.
结直肠癌肝转移很常见，对于不适合手术切除的特定患者，消融治疗是一种不错的治疗选择。本研究旨在系统回顾文献，并呈现经皮超声引导下消融治疗后与生存及局部复发相关的预后因素。
本综述按照PRISMA报告。检索了PubMed、Embase和Scopus，记录由两位作者独立筛选，最初根据标题和摘要，随后基于全文进行筛选。使用纽卡斯尔-渥太华质量评估量表评估研究质量。
在筛选的2882条记录中，纳入了18项研究。中位生存期为23个月。1年生存率中位数为95%，3年生存率中位数为58%。完全消融反应和辅助化疗可显著提高生存率并降低局部复发率。
经皮超声引导下的消融技术治疗结直肠癌肝转移，为不适合手术切除的患者提供了令人印象深刻的生存率。然而，存在一些与预后较差相关的因素，在选择患者时可予以考虑。
