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单侧原发性卵巢平滑肌瘤伪装成卵巢纤维瘤:组织病理学诊断

Unilateral primary ovarian leiomyoma masqueraded as ovarian fibroma: A histopathological diagnosis.

作者信息

Bharti Sushma, Khera Sudeep, Sharma Charu, Balakrishnan Arsha

机构信息

Department of Pathology, AIIMS, Jodhpur, Rajasthan, India.

Department of Obstetrics and Gynecology, AIIMS, Jodhpur, Rajasthan, India.

出版信息

J Family Med Prim Care. 2021 Sep;10(9):3494-3497. doi: 10.4103/jfmpc.jfmpc_2546_20. Epub 2021 Jun 30.

DOI:10.4103/jfmpc.jfmpc_2546_20
PMID:34760779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8565167/
Abstract

Leiomyoma is the commonest benign mesenchymal tumor of the uterus, which can be developed at any site where smooth muscle cells are found. The broad ligament is the most common and ovary is one of the rarest extrauterine sites, accounting for 0.5-1% of all benign ovarian tumors. Herein, we report a case of ovarian leiomyoma in a perimenopausal female, clinically presented with heavy menstrual bleed, radiologically diagnosed as subserosal uterine fibroid. Intraoperatively, it was considered as ovarian fibroma but finally diagnosed as ovarian leiomyoma on histomorphology, which was confirmed on special stains and immunohistochemistry. A review of literature showed that less than 100 cases of primary ovarian leiomyomata have been reported until now. Ovarian leiomyoma is usually small, asymptomatic, and an incidental finding mostly, usually synchronously seen with uterine leiomyoma. Ovarian leiomyoma is a rare tumor, often misdiagnosed prior to surgical removal and it should be differentiated from other spindle cell neoplasm and solid tumors of the ovary.

摘要

平滑肌瘤是子宫最常见的良性间叶组织肿瘤,可发生于任何有平滑肌细胞的部位。阔韧带是最常见的部位,而卵巢是最罕见的子宫外部位之一,占所有良性卵巢肿瘤的0.5 - 1%。在此,我们报告一例围绝经期女性的卵巢平滑肌瘤,临床症状为月经过多,影像学诊断为浆膜下子宫肌瘤。术中,最初考虑为卵巢纤维瘤,但最终经组织形态学诊断为卵巢平滑肌瘤,并通过特殊染色和免疫组织化学得以证实。文献回顾显示,迄今为止报道的原发性卵巢平滑肌瘤病例不足100例。卵巢平滑肌瘤通常较小,无症状,大多为偶然发现,常与子宫平滑肌瘤同时出现。卵巢平滑肌瘤是一种罕见肿瘤,在手术切除前常被误诊,应与卵巢其他梭形细胞瘤和实体瘤相鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/b7d7cf02aef7/JFMPC-10-3494-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/2d750d09e938/JFMPC-10-3494-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/bf8b0a82e545/JFMPC-10-3494-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/39f48208b6ab/JFMPC-10-3494-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/a8e416a4bb29/JFMPC-10-3494-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/f184faa8bdb5/JFMPC-10-3494-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/08dbc195cdd4/JFMPC-10-3494-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/b7d7cf02aef7/JFMPC-10-3494-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/2d750d09e938/JFMPC-10-3494-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/bf8b0a82e545/JFMPC-10-3494-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/39f48208b6ab/JFMPC-10-3494-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/a8e416a4bb29/JFMPC-10-3494-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/f184faa8bdb5/JFMPC-10-3494-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/08dbc195cdd4/JFMPC-10-3494-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6da7/8565167/b7d7cf02aef7/JFMPC-10-3494-g007.jpg

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本文引用的文献

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Symptomatic Primary Ovarian Leiomyoma in a Postmenopausal Woman: A Rare Entity.一名绝经后女性的症状性原发性卵巢平滑肌瘤:一种罕见病例
J Midlife Health. 2020 Jul-Sep;11(3):175-177. doi: 10.4103/jmh.JMH_105_19. Epub 2020 Sep 29.
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A huge primary ovarian leiomyoma with degenerative changes-an unusual.一例伴有退行性变的巨大原发性卵巢平滑肌瘤——罕见病例
J Clin Diagn Res. 2013 Jun;7(6):1152-4. doi: 10.7860/JCDR/2013/5313.3060. Epub 2013 Jun 1.
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Primary ovarian leiomyoma: a rare cause of ovarian tumor in adolescence.原发性卵巢平滑肌瘤:青少年卵巢肿瘤的罕见病因。
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