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腹主动脉瘤与冠状动脉疾病:是否需要采取更积极的治疗方法?

Abdominal aortic aneurysms and coronary artery disease: is a more aggressive approach indicated?

作者信息

Hall R, Coupland G, Lane R, Appleberg M

出版信息

Aust N Z J Surg. 1987 May;57(5):311-5. doi: 10.1111/j.1445-2197.1987.tb01364.x.

Abstract

A retrospective study was undertaken to assess the influence of known ischaemic heart disease on the operative and the long-term survival of patients undergoing elective repair of an abdominal aortic aneurysm. One hundred and seventy-one patients underwent elective surgery between June 1977 and December 1983. The patients were divided on routine clinical grounds into cardiac and noncardiac groups. Ninety-five patients had a history of heart disease and/or an abnormal resting pre-operative ECG. Seventy-six patients had no history of heart disease and a normal pre-operative resting ECG. Two of the seven operative deaths were due to myocardial infarction with one each from the cardiac and noncardiac groups. Eight patients suffered an acute myocardial infarction with five from the cardiac and three from the noncardiac group and this was not significantly different. The overall survival of 95% at 1 year and 76% at 5 years closely follows the age/sex matched Australian population. The survival at 1 year in the cardiac group was 97% and 95% in the noncardiac group. The 5 year survival was 72% and 79% respectively. During follow-up to December 1984, 11 patients died from ischaemic heart disease with six from the cardiac and five from the noncardiac group. No significant difference was found between the two groups in the incidence of myocardial infarction or the short- and long-term survival. This study does not support a more aggressive approach to coronary artery disease in the pre-operative management of patients with abdominal aortic aneurysm.

摘要

进行了一项回顾性研究,以评估已知缺血性心脏病对接受腹主动脉瘤择期修复手术患者的手术及长期生存的影响。1977年6月至1983年12月期间,171例患者接受了择期手术。根据常规临床标准,将患者分为心脏疾病组和非心脏疾病组。95例患者有心脏病史和/或术前静息心电图异常。76例患者无心脏病史且术前静息心电图正常。7例手术死亡患者中有2例死于心肌梗死,心脏疾病组和非心脏疾病组各1例。8例患者发生急性心肌梗死,心脏疾病组5例,非心脏疾病组3例,两组之间无显著差异。1年总体生存率为95%,5年为76%,与年龄/性别匹配的澳大利亚人群相近。心脏疾病组1年生存率为97%,非心脏疾病组为95%。5年生存率分别为72%和79%。在随访至1984年12月期间,11例患者死于缺血性心脏病,心脏疾病组6例,非心脏疾病组5例。两组在心肌梗死发生率或短期和长期生存率方面未发现显著差异。本研究不支持在腹主动脉瘤患者术前管理中对冠状动脉疾病采取更积极的治疗方法。

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