Yoon Hong-Gyu, Ko Yong, Kim Young-Soo, Bak Koang-Hum, Chun Hyoung-Joon, Na Min-Kyun, Yang Sook, Yi Hyeong-Joong, Choi Kyu-Sun
Department of Neurosurgery, College of Medicine, Hanyang University, Seoul, Korea.
CUSMEDI Co., Ltd., Suwon, Korea.
Korean J Neurotrauma. 2021 Sep 9;17(2):91-99. doi: 10.13004/kjnt.2021.17.e25. eCollection 2021 Oct.
Autologous bone grafting for cranioplasty is associated with a high infection rate and bone absorption. Synthetic implant materials for cranioplasty have been developed. In this study, we evaluated the efficacy of titanium mesh-type patient-specific implants (PSIs) for patients with skull defects using the dice similarity coefficient (DSC), clinical outcomes, and artifacts caused by implants.
This retrospective study included 40 patients who underwent cranioplasty with a titanium mesh PSI at our institution. Based on preoperative and postoperative computed tomography scans, we calculated DSC and artifacts.
The calculated DSC of 40 patients was 0.75, and the noise was 13.89% higher in the region of interest (ROI) near the implanted side (average, 7.64 hounsfield unit [HU]±2.62) than in the normal bone (average, 6.72 HU±2.35). However, the image signal-to-noise ratio did not significantly differ between the ROI near the implanted side (4.77±1.78) and normal bone (4.97±1.88). The patients showed no significant perioperative complications that required a secondary operation.
Titanium mesh-type PSIs for cranioplasty have excellent DSC values with lower artifacts and complication rates.
自体骨移植用于颅骨成形术的感染率高且存在骨吸收现象。现已开发出用于颅骨成形术的合成植入材料。在本研究中，我们使用骰子相似系数（DSC）、临床结果以及植入物引起的伪影，评估了钛网型定制植入物（PSI）对颅骨缺损患者的疗效。
这项回顾性研究纳入了在我们机构接受钛网PSI颅骨成形术的40例患者。基于术前和术后的计算机断层扫描，我们计算了DSC和伪影。
40例患者计算出的DSC为0.75，植入侧附近感兴趣区域（ROI）的噪声比正常骨高13.89%（平均，7.64亨氏单位[HU]±2.62），而正常骨平均为6.72 HU±2.35。然而，植入侧附近ROI（4.77±1.78）与正常骨（4.97±1.88）之间的图像信噪比无显著差异。患者未出现需要二次手术的明显围手术期并发症。
用于颅骨成形术的钛网型PSI具有优异的DSC值，伪影和并发症发生率较低。
