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Phase II study of idarubicin administered i.v. to pediatric patients with acute lymphoblastic leukemia.

作者信息

Madon E, Grazia G, De Bernardi B, Comelli A, Carli M, Sainati L, Paolucci G, Canino R, Colella R, Bagnulo S

出版信息

Cancer Treat Rep. 1987 Sep;71(9):855-6.

PMID:3476202
Abstract

A total of 17 pediatric patients with pretreated acute lymphoblastic leukemia were included in a phase II study of idarubicin. Four of 16 complete remissions were obtained, confirming the activity of the drug in this indication. Toxicity was acceptable, though caution is needed in patients who have already received high cumulative doses of anthracyclines.

摘要

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引用本文的文献

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Br J Cancer. 1995 Jun;71(6):1188-93. doi: 10.1038/bjc.1995.231.
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Idarubicin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer.
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Drugs. 1991 Oct;42(4):690-719. doi: 10.2165/00003495-199142040-00010.