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本文引用的文献

1
Durable remissions following combined targeted therapy in patients with CLL harboring TP53 deletions and/or mutations.在伴有 TP53 缺失和/或突变的 CLL 患者中,联合靶向治疗后可获得持久缓解。
Blood. 2021 Nov 11;138(19):1805-1816. doi: 10.1182/blood.2020010484.
2
Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3 trial.维奈托克联合奥滨尤妥珠单抗与苯丁酸氮芥联合奥滨尤妥珠单抗治疗初治慢性淋巴细胞白血病(CLL14):一项多中心、开放标签、随机、3 期临床试验的随访结果。
Lancet Oncol. 2020 Sep;21(9):1188-1200. doi: 10.1016/S1470-2045(20)30443-5.
3
Ibrutinib for Chronic Lymphocytic Leukemia with Alterations.伊布替尼用于治疗伴有改变的慢性淋巴细胞白血病。
N Engl J Med. 2020 Jul 30;383(5):498-500. doi: 10.1056/NEJMc2005943.
4
Ibrutinib and Venetoclax for First-Line Treatment of CLL.伊布替尼联合维奈托克用于初治 CLL 患者。
N Engl J Med. 2019 May 30;380(22):2095-2103. doi: 10.1056/NEJMoa1900574.
5
Venetoclax for Patients With Chronic Lymphocytic Leukemia With 17p Deletion: Results From the Full Population of a Phase II Pivotal Trial.维奈托克治疗伴有 17p 缺失的慢性淋巴细胞白血病患者:来自 II 期关键性试验全人群的结果。
J Clin Oncol. 2018 Jul 1;36(19):1973-1980. doi: 10.1200/JCO.2017.76.6840. Epub 2018 May 1.
6
CLL2-BXX Phase II trials: sequential, targeted treatment for eradication of minimal residual disease in chronic lymphocytic leukemia.CLL2-BXX 二期临床试验:慢性淋巴细胞白血病微小残留病灶消除的序贯靶向治疗。
Future Oncol. 2018 Mar;14(6):499-513. doi: 10.2217/fon-2017-0442. Epub 2018 Feb 21.
7
Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.慢性淋巴细胞白血病的基因突变与治疗结果:CLL8 试验结果。
Blood. 2014 May 22;123(21):3247-54. doi: 10.1182/blood-2014-01-546150. Epub 2014 Mar 20.
8
Signaling the end of chronic lymphocytic leukemia: new frontline treatment strategies.宣告慢性淋巴细胞白血病的终结:新的一线治疗策略
Hematology Am Soc Hematol Educ Program. 2013;2013:138-50. doi: 10.1182/asheducation-2013.1.138.
9
The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of Del17p13: implications for overall survival and chemorefractoriness.TP53突变在慢性淋巴细胞白血病中的预后价值独立于17p13缺失:对总生存期和化疗难治性的影响
Clin Cancer Res. 2009 Feb 1;15(3):995-1004. doi: 10.1158/1078-0432.CCR-08-1630.

Improving the outlook for TP53-aberrant CLL.

作者信息

Choi Michael Y

机构信息

University of California San Diego Moores Cancer Center.

出版信息

Blood. 2021 Nov 11;138(19):1785-1786. doi: 10.1182/blood.2021012759.

DOI:10.1182/blood.2021012759
PMID:34762129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9642792/
Abstract
摘要