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心境障碍和注意缺陷多动障碍青少年的环性-敏感气质评估。

The assessment of cyclothymic-hypersensitive temperament in youth with mood disorders and attention deficit hyperactivity disorder.

机构信息

Department of Translational Medical Sciences, University of Naples Federico II, via Pansini 5, Naples 80131, Italy.

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; IRCCS Fondazione Stella Maris, Scientific Institute of Child Neurology and Psychiatry, Calambrone, Pisa, Italy.

出版信息

J Affect Disord. 2022 Feb 1;298(Pt A):322-328. doi: 10.1016/j.jad.2021.11.013. Epub 2021 Nov 9.

Abstract

BACKGROUND

Cyclothymic-hypersensitive temperament (CHT) has been related to both depression and bipolarity, as well as to suicidality. Recently, a psychometrically sound way of assessment has been validated in youth (Cyclothymic-Hypersensitive Temperament Questionnaire, CHTQ), but data on clinical populations are still scant. Aim of our study is to further explore the structure and other psychometric properties of the revised version of CHTQ and its clinical implications in clinical samples.

METHODS

The study is based on a dataset of patients with unipolar depression, bipolar disorder and attention deficit and hyperactivity disorder (ADHD) (243 patients, 135 males, mean age 14.22 ± 2.16 years, age range 9-18 years), compared to a community sample of adolescents (398 subjects, 95 boys, mean age 15.47 ± 1.96 years, age range 10-18 years) RESULTS: The two-correlated factor structure of CHT has been confirmed, with a moodiness/hypersensitiveness factor, correlated with internalizing symptoms, and an impulsiveness/emotional dysregulation factor, correlated with externalizing symptoms. All CHTQ scores correlate with global functioning. CHTQ total scores discriminate patients from healthy controls. Only CHTQ impulsiveness/emotional dysregulation subscale score is higher in bipolar patients, compared to unipolar depression and ADHD, whereas neither CHTQ moodiness/hypersensitiveness subscale score nor CHTQ total score discriminate between clinical groups.

LIMITATION

Data on current mood states are unavailable. Patients were recruited in a third level clinic. The unipolar depression group is relatively small.

CONCLUSION

CHT may be a rapid and reliable screening and diagnostic tool in the clinical practice with youth, exploring the cyclothymic dimension in different psychiatric disorders.

摘要

背景

环性敏感气质(CHT)与抑郁和双相障碍以及自杀有关。最近,一种在年轻人中具有良好心理测量学效度的评估方法已经得到验证(环性敏感气质问卷,CHTQ),但关于临床人群的数据仍然很少。我们的研究目的是进一步探索 CHTQ 修订版的结构和其他心理测量学特性及其在临床样本中的临床意义。

方法

该研究基于一组单相抑郁、双相障碍和注意缺陷多动障碍(ADHD)患者的数据(243 例患者,135 例男性,平均年龄 14.22±2.16 岁,年龄范围 9-18 岁),与青少年社区样本(398 例受试者,95 例男性,平均年龄 15.47±1.96 岁,年龄范围 10-18 岁)进行比较。

结果

CHT 的双相关因素结构得到了证实,包括情绪多变/敏感因子,与内化症状相关,以及冲动/情绪失调因子,与外化症状相关。所有 CHTQ 评分均与整体功能相关。CHTQ 总分可区分患者与健康对照组。只有双相障碍患者的 CHTQ 冲动/情绪失调子量表评分高于单相抑郁和 ADHD,而 CHTQ 情绪多变/敏感子量表评分或 CHTQ 总分均不能区分临床组。

局限性

目前的情绪状态数据不可用。患者是在三级诊所招募的。单相抑郁组相对较小。

结论

CHT 可能是一种快速、可靠的筛查和诊断工具,可用于临床实践中的年轻人,探索不同精神障碍中的环性维度。

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