Institute of Dermatology and Venereology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China; Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China.
Ann Palliat Med. 2021 Oct;10(10):10674-10683. doi: 10.21037/apm-21-2386.
To clarify the efficacy and safety of traditional Chinese medicine (TCM) bath in the treatment of psoriasis vulgaris, meta-analysis and systematic evaluation were adopted to comprehensively evaluate the published articles.
Combing the terms "traditional Chinese medicine bath" and "psoriasis vulgaris", the articles were searched for in the databases of China Knowledge Network (CNKI), Baidu scholar, Wanfang, Chinese Biomedical Literature Database (CBM), Weipu Database, Medline, Embase, Chinese Medical Citation Index (CMCI), and PubMed. The quality of articles was evaluated using the RevMan 5.3 software provided by the Cochrane system.
A total of 13 articles were included. From the funnel chart drawn, it could be seen that the circles and the midline of most articles were not symmetrical, and the publication was biased, so the conclusions obtained were relatively credible. The heterogeneity analysis of TCM bath in treatment of psoriasis vulgaris showed that 13 articles reporting the total effective rate (TER) and the TERs of the two groups displayed obvious differences [P<0.05, 95% confidence interval (CI): 2.9 to 4.77]; there were 8 articles reporting the incidence of adverse reactions, and the incidence of adverse reactions between the two groups was greatly different (P<0.05, 95% CI: 0.22 to 0.77); and there were 9 articles reporting the psoriasis area and severity index, and the overall efficacy was greatly different between the two groups (P<0.05, 95% CI: -5.38 to -1.88).
The TER of the meta-analysis of treatment in this study was higher in the experimental group; the incidence of adverse reactions was lower in the experimental group; and the area and severity of psoriasis were lower in the experimental group, so it was concluded that the TCM bath had a significant effect on the treatment of psoriasis vulgaris.
为了阐明中药浴治疗寻常型银屑病的疗效和安全性，采用荟萃分析和系统评价对已发表的文献进行综合评价。
在中国知网（CNKI）、百度学术、万方、中国生物医学文献数据库（CBM）、维普数据库、PubMed、Embase、中国医学引文数据库（CMCI）和PubMed 中，分别检索“中药浴”和“寻常型银屑病”的相关文章。采用 Cochrane 系统提供的 RevMan 5.3 软件评价文献质量。
共纳入 13 篇文献。从绘制的漏斗图可以看出，大多数文章的圆圈与中线并不对称，存在发表偏倚，因此获得的结论相对可靠。中药浴治疗寻常型银屑病的总有效率（TER）及两组 TER 异质性分析显示，13 篇报道 TER 的文章差异有统计学意义[P<0.05，95%置信区间（CI）：2.9 至 4.77]；8 篇报道不良反应发生率的文章显示，两组不良反应发生率差异有统计学意义（P<0.05，95% CI：0.22 至 0.77）；9 篇报道银屑病面积和严重程度指数的文章显示，两组总体疗效差异有统计学意义（P<0.05，95% CI：-5.38 至-1.88）。
本研究治疗的荟萃分析中，实验组的 TER 较高；实验组不良反应发生率较低；实验组银屑病面积和严重程度指数较低，因此可以得出结论，中药浴对寻常型银屑病的治疗有显著疗效。
