Department of Orthopedics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Orthopedic Laboratory of Chongqing Medical University, Chongqing, China.
Department of Orthopedics, Cangnan Hospital of Traditional Chinese Medicine, Wenzhou, China.
Ann Palliat Med. 2021 Oct;10(10):11013-11023. doi: 10.21037/apm-21-2767.
To investigate the effect of bone cement on the curative effect of percutaneous kyphoplasty (PKP) in the treatment of osteoporotic vertebral compression fracture (OVCF).
A total of 323 patients with OVCF who underwent PKP in our hospital between January 2018 and June 2020 were enrolled. According to the viscosity and distribution of the bone cement, the patients were divided into a high viscosity (HV) group and a low viscosity (LV) group, and into a central distribution (central) group and a lateral distribution (lateral) group, and their baseline characteristics, perioperative parameters, efficacy indicators, and complications indicators were compared.
In the HV group, the amount of bone cement injected and the number of patients with centrally distributed bone cement were significantly higher than those in the LV group, while the operation time and the number of patients with laterally distributed bone cement were significantly lower. Further, the bone cement viscosity in the central group was significantly higher than that in the lateral group. Before surgery, there were no significant differences between the groups in terms of the posterior back visual analog scale (VAS) score, Oswestry dysfunction index (ODI), Cobb angle, vertebral height, or anterior vertebral height (AVH) of the fractured vertebral body. However, after surgery, both the ODI and the Cobb angle were notably reduced and the AVH was increased in the HV group. Meanwhile, in the central group, the VAS, Cobb angle, and ODI were all dramatically reduced.
Centrally distributed high-viscosity bone cement can reduce the Cobb angle and the incidence of bone cement leakage in patients with OVCF who undergo PKP, thereby improving the curative effect.
研究骨水泥对经皮椎体后凸成形术（PKP）治疗骨质疏松性椎体压缩性骨折（OVCF）疗效的影响。
选取我院 2018 年 1 月至 2020 年 6 月行 PKP 治疗的 OVCF 患者 323 例，根据骨水泥的黏度和分布情况分为高黏度（HV）组和低黏度（LV）组、中央分布（中央）组和外侧分布（外侧）组，比较其一般资料、围手术期参数、疗效指标和并发症指标。
HV 组注入骨水泥量、中央分布骨水泥患者数明显多于 LV 组，手术时间、外侧分布骨水泥患者数明显少于 LV 组；中央组骨水泥黏度明显高于外侧组。术前各组患者的后背部视觉模拟评分（VAS）、Oswestry 功能障碍指数（ODI）、Cobb 角、椎体高度、骨折椎体前缘高度（AVH）比较，差异均无统计学意义；术后 HV 组 ODI、Cobb 角均明显降低，AVH 明显升高，中央组 VAS、Cobb 角、ODI 均明显降低。
经皮椎体后凸成形术中应用中央分布的高黏度骨水泥可降低 OVCF 患者的 Cobb 角和骨水泥渗漏发生率，从而提高疗效。
