Department of Diagnostic Radiology, Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Center for Fast Ultrasound Imaging, Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Ultrasound Med Biol. 2022 Feb;48(2):346-357. doi: 10.1016/j.ultrasmedbio.2021.10.004. Epub 2021 Nov 9.
Local pressure differences estimated using vector flow imaging (VFI) and direct catheterization in seven carotid bifurcation phantoms were compared with simulated pressure fields. VFI correlated strongly with simulated peak pressure differences (r = 0.99, p < 0.00001), with an average overestimation of 12.3 Pa (28.6%). The range between the lowest and highest pressure difference of VFI underestimated simulations by 4.6 Pa (8.06%; r = 0.99, p < 0.0001). The catheter method exhibited no correlation (r = -0.09, p = 0.85). Ten repeated measurements on one phantom revealed a small standard deviation (SD) for VFI (SD = 8.4%, mean estimated SD = 11.5%), but not for the catheter method (SD = 785.6%). An in vivo peak systolic pressure difference of 97.9 Pa (estimated SD = 30%) was measured using VFI in one healthy individual. This study indicates that VFI pressure difference estimation is feasible in phantoms and in vivo and realistic estimates of the SD can be attained from the data.
使用血流向量成像（VFI）和直接导管法在 7 个颈动脉分叉体模中估计的局部压力差与模拟压力场进行了比较。VFI 与模拟的峰值压力差相关性很强（r = 0.99，p < 0.00001），平均高估了 12.3 Pa（28.6%）。VFI 最低和最高压力差之间的差值低估了模拟值 4.6 Pa（8.06%；r = 0.99，p < 0.0001）。导管法无相关性（r = -0.09，p = 0.85）。在一个体模上进行的 10 次重复测量显示 VFI 的标准差较小（SD = 8.4%，估计的平均 SD = 11.5%），但导管法的标准差较大（SD = 785.6%）。在一个健康个体中，使用 VFI 测量到的收缩期峰值压力差为 97.9 Pa（估计的 SD = 30%）。本研究表明，VFI 压力差估计在体模和体内是可行的，并且可以从数据中获得 SD 的实际估计值。
