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Phosphoproteomics reveals therapeutic targets of esophageal squamous cell carcinoma.

作者信息

Li Yi, Yang Bin, Ma Yanchun, Peng Xiaojun, Wang Zhiyu, Sheng Bin, Wei Zichao, Cui Yongping, Liu Zhihua

机构信息

State Key Lab of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.

Department of Pathology, Key Laboratory of Cellular Physiology (Shanxi Medical University), Ministry of Education, Taiyuan, 030001, Shanxi, China.

出版信息

Signal Transduct Target Ther. 2021 Nov 12;6(1):381. doi: 10.1038/s41392-021-00682-5.

DOI:10.1038/s41392-021-00682-5
PMID:34764241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8585941/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f60/8585941/4f424424cb40/41392_2021_682_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f60/8585941/4f424424cb40/41392_2021_682_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f60/8585941/4f424424cb40/41392_2021_682_Fig1_HTML.jpg

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Phosphoproteomics profiling of sorafenib-resistant hepatocellular carcinoma patient-derived xenografts reveals potential therapeutic strategies.索拉非尼耐药的肝癌患者来源异种移植瘤的磷酸化蛋白质组学分析揭示了潜在的治疗策略。
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Proteomic and phosphoproteomic landscape of localized prostate cancer unveils distinct molecular subtypes and insights into precision therapeutics.局部前列腺癌的蛋白质组学和磷酸化蛋白质组学全景揭示了不同的分子亚型,并深入了解精准治疗。
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