Larsen M J, Kirkegaard E, Poulsen S
J Dent Res. 1987 Jan;66(1):10-2. doi: 10.1177/00220345870660010101.
Dental fluorosis among 456 14-16-year-old schoolchildren who had resided continuously since birth in their respective study areas was recorded using the Thylstrup and Fejerskov classification system. The children fell into four groups according to fluoride concentration of their drinking water: (1) less than or equal to 0.1 ppm; (2) 0.3-0.5 ppm; (3) 0.5-1.25 ppm; and (4) 1.26-2.0 ppm. It was found that the later in childhood the tooth was formed, the higher was the prevalence of dental fluorosis. The fluoride concentration in the drinking water affected the prevalence of dental fluorosis in all teeth except the lower incisors, which are formed very early in life. Apart from these teeth, the proportionate increase of dental fluorosis with increasing water fluoride concentration was almost the same for all tooth types. However, the actual amount of increase in the prevalence and degree of fluorosis was greatest among those teeth that formed later during childhood. The observed fluorosis is presumed to result from and reflect the drinking water habits in the population as well as the patterns of use of fluoride prophylactics.
采用蒂尔斯楚普和费耶斯科夫分类系统,记录了456名自出生起就一直居住在各自研究区域的14至16岁学童的氟斑牙情况。根据饮用水中的氟化物浓度,这些儿童被分为四组:(1)小于或等于0.1 ppm;(2)0.3 - 0.5 ppm;(3)0.5 - 1.25 ppm;以及(4)1.26 - 2.0 ppm。研究发现,牙齿形成的时间越晚,氟斑牙的患病率越高。饮用水中的氟化物浓度影响了除下切牙(其在生命早期就已形成)之外所有牙齿的氟斑牙患病率。除了这些牙齿,对于所有牙型而言,随着水中氟化物浓度的增加,氟斑牙的相应增加比例几乎相同。然而,氟斑牙患病率和严重程度的实际增加量在儿童期后期形成的牙齿中最为显著。观察到的氟斑牙被认为是由人群的饮用水习惯以及氟化物预防剂的使用模式导致的,并反映了这些情况。