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胰体尾切除术:血管对吻合口完整性的意义及重建技术要点

Central Pancreatectomy: Significance of Vascularity on Anastomotic Integrity and a Note on Reconstructive Technique.

作者信息

Girish Suraj, Kapil Nagaraj, Kannan Naveen

机构信息

General Surgery, Meenakshi Medical College and Research Institute, Kanchipuram, IND.

Surgical Gastroenterology, Meenakshi Medical College and Research Institute, Kanchipuram, IND.

出版信息

Cureus. 2021 Oct 8;13(10):e18617. doi: 10.7759/cureus.18617. eCollection 2021 Oct.

DOI:10.7759/cureus.18617
PMID:34765372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8573194/
Abstract

Central pancreatectomy is a pancreatic parenchymal sparing surgery usually indicated for benign and borderline malignant tumors of the neck and proximal body of the pancreas. Due to the presence of extensive intra-pancreatic spread, pancreatic parenchyma sparing procedures such as central pancreatectomy are invariably deferred in pancreatic malignancy. The need for management of two pancreatic stumps with a usually soft texture and non-dilated ducts, given the indications, increases the risk of pancreatic fistula and therefore morbidity. Proximal stump management is usually a closure either by suture or stapler with reinforcements; the technique preferred depends on the experience of the surgeon and is mostly extrapolated from distal pancreatectomy. Distal stump management is the Achilles' heel owing to the texture of the pancreas and pancreatic duct size. Need for additional mobilization may have a bearing on the perfusion of the pancreatic stump and hence may lead to clinically relevant leaks. The use of octreotide accentuating the said vascular insufficiency may not be an overstatement. Here we present a case of solid pseudopapillary tumor (SPT) of the neck and proximal body of the pancreas in which a central pancreatectomy with falciform patch closure of the proximal stump and binding pancreaticogastrostomy (PG) was contemplated and further we discuss the types of reconstruction with special reference to the vascular pattern of distal pancreas.

摘要

胰体尾切除术是一种保留胰腺实质的手术,通常适用于胰腺颈部和胰体近端的良性及交界性恶性肿瘤。由于胰腺内广泛扩散的存在,对于胰腺恶性肿瘤,诸如胰体尾切除术等保留胰腺实质的手术总是被推迟。鉴于手术指征,需要处理两个质地通常较软且导管未扩张的胰腺残端,这增加了胰瘘的风险,进而增加了发病率。近端残端的处理通常是用缝线或吻合器进行缝合,并辅以加固;所选用的技术取决于外科医生的经验,且大多是从胰头十二指肠切除术推断而来。由于胰腺的质地和胰管大小,远端残端的处理是关键难题。额外游离的需求可能会影响胰腺残端的血供,从而可能导致具有临床意义的渗漏。使用奥曲肽加剧上述血管不足或许并非言过其实。在此,我们呈现一例胰腺颈部和胰体近端的实性假乳头状瘤(SPT)病例,该病例考虑进行胰体尾切除术,近端残端采用镰状补片缝合,并行捆绑式胰胃吻合术(PG),此外,我们还特别参照胰腺远端的血管模式讨论了重建类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f337/8573194/df390aef86c9/cureus-0013-00000018617-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f337/8573194/496fb286ad5e/cureus-0013-00000018617-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f337/8573194/df390aef86c9/cureus-0013-00000018617-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f337/8573194/496fb286ad5e/cureus-0013-00000018617-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f337/8573194/df390aef86c9/cureus-0013-00000018617-i02.jpg

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Ann Hepatobiliary Pancreat Surg. 2023 Feb 28;27(1):87-94. doi: 10.14701/ahbps.22-042. Epub 2022 Nov 22.

本文引用的文献

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Central pancreatectomy: a comprehensive, up-to-date meta-analysis.胰体中部切除术:一项全面、最新的荟萃分析。
Langenbecks Arch Surg. 2019 Dec;404(8):945-958. doi: 10.1007/s00423-019-01829-3. Epub 2019 Oct 22.
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The Arterial Supply of the Distal Part of the Pancreas.胰腺远端的动脉供应
Surg Res Pract. 2019 Mar 20;2019:5804047. doi: 10.1155/2019/5804047. eCollection 2019.
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Pancreatic stump closure techniques and pancreatic fistula formation after distal pancreatectomy: Meta-analysis and single-center experience.
胰尾部切除术后胰腺残端闭合技术与胰瘘形成:荟萃分析和单中心经验。
PLoS One. 2018 Jun 13;13(6):e0197553. doi: 10.1371/journal.pone.0197553. eCollection 2018.
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Postoperative pancreatic fistula: a review of traditional and emerging concepts.术后胰瘘:传统概念与新观点综述
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Benign Tumors of the Pancreas-Radical Surgery Versus Parenchyma-Sparing Local Resection-the Challenge Facing Surgeons.胰腺良性肿瘤——根治性手术与保留实质的局部切除术——外科医生面临的挑战。
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Different types of pancreatico-enteric anastomosis.不同类型的胰肠吻合术。
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Pancreatic anastomosis after pancreatoduodenectomy: A position statement by the International Study Group of Pancreatic Surgery (ISGPS).胰十二指肠切除术后的胰腺吻合术:国际胰腺手术研究组(ISGPS)的立场声明
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Defining the practice of pancreatoduodenectomy around the world.界定全球范围内胰十二指肠切除术的实施情况。
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